Beetroot Juice and Sleep

Effects of Nocturnal Inorganic Nitrate Supplementation on Physiological Function

The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.

Inclusion Criteria:

• 18-35 or 65-80 years of age

Exclusion Criteria:

• Coronary artery disease
• Heart failure
• Pregnancy
• Diabetes
• Sleep disorders
• Shift workers
• Individuals who typically go to sleep after midnight
• Individuals who traveled across ≥2 time zones within one week of study visits
• Individuals with a history frequent kidney stones
• BMI ≥35.0kg/m2
• Use of nicotine-containing products within the two years preceding study visits
• Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures