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The purpose of current study is to evaluate the efficacy and safety of hetrombopag for the treatment of chemotherapy-induced thrombocytopenia in patients with solid tumors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hetrombopag | Experimental |
| |
| Hetrombopag plus Placebo | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hetrombopag | Drug | Hetrombopag |
| |
| Hetrombopag plus Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| The proportion of treatment responders. | Randomization up to 80 days |
| Measure | Description | Time Frame |
|---|---|---|
| Duration from the commencement of treatment to a platelet count ≥100×109/L; | Randomization up to 30 days | |
| Proportion of subjects who could complete chemotherapy without dose modification and rescue therapy and; | Randomization up to 160 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hematology Tumor Research Center of Harbin First Hospital | Haerbin | Heilongjiang | 150000 | China |
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| ID | Term |
|---|---|
| C000614661 | hetrombopag |
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| Drug |
Hetrombopag plus Placebo |
|
| Placebo | Drug | Placebo |
|
| Proportion of subjects without serious bleeding events; | Randomization up to 190 days |
| Number of adverse events (AEs)/serious adverse events (SAEs) | Randomization up to 190 days |