The goal of this clinical trial is to evaluate the diagnostic yield of CADe in a consecutive population undergoing colonoscopy. The main question it aims to answer is the Adenoma Detection Rate (ADR). Participants undergoing colonoscopy will be randomized in a 1:1 ratio to either receive Computer-Aided Detection (CADe) colonoscopy or a conventional colonoscopy (CC). Researchers will compare the CADe group and the CC-group to see if CAD-e can increase the ADR significantly.

Inclusion Criteria:

• Age ≥ 18 years or ≤85
• Patients undergoing screening, follow-up, or diagnostic colonoscopy

Exclusion Criteria:

• Suspected or known inflammatory bowel disease
• Colonic resection
• Taking anticoagulants or antiaggregants that contraindicate the performance of therapy
• Patients with incomplete colonoscopy
• Patients with inadequate preparation using the Boston Colonic Preparation Scale (BBPS). A cleaning quality of less than 2 points in any of the 3 colonic sections will be considered inadequate.
• Inability to provide informed consent.