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The main goal of the Liver Biomarkers in Anorexia Nervosa (LIBAN) study is to determine the prevalence of liver fibrosis in patient with Anorexia Nervosa.
Prevalence of hepatic fibrosis will be non-invasively investigated, in the Anorexia Nervosa inpatient population, using the Fibroscan ®. Furthermore, liver blood markers will be assessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non applicable (NA) | Patients with Anorexia Nervosa hospitalized for malnutrition |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fibroscan | Diagnostic Test | Fibroscan is a non-invasive device that allows liver exploration painlessly, quickly (a few minutes) and with immediate results. A probe placed on the skin generates an elastic wave completely painlessly and the device measures its speed of propagation in the liver. Liver stiffness is calculated from this speed. |
| Measure | Description | Time Frame |
|---|---|---|
| Liver fibrosis prevalence in patients with Anorexia nervosa | Liver stiffness will be assessed using Fibroscan (kPA) within the 24 hours following admission to the endocrinology, diabetology and nutrition department. | Day one |
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Inclusion Criteria :
Exclusion Criteria :
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Consecutive inclusion of patients hospitalized in the endocrinology department for anorexia nervosa with malnutrition criteria.
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| Name | Affiliation | Role |
|---|---|---|
| Sarra SMATI-GRANGEON, PH | Nantes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nantes University Hospital | Nantes | Loire-Atlantique | 44093 | France |
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| ID | Term |
|---|---|
| D000856 | Anorexia Nervosa |
| D008103 | Liver Cirrhosis |
| D005234 | Fatty Liver |
| ID | Term |
|---|---|
| D001068 | Feeding and Eating Disorders |
| D001523 | Mental Disorders |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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These are blood samples that may be used for further research.
|
| D005355 |
| Fibrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |