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Tissue and serum samples from 20 MF patients and 20 normal healthy controls will be subjected for biochemical assessments by ELISA (Enzyme- linked immune-sorbent assay) for assessing the level of IL35.
Tissue and serum samples from 20 MF patients and 20 normal healthy controls will be subjected for biochemical assessments by ELISA (Enzyme- linked immune-sorbent assay) for assessing the level of IL35
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mycosis fungoides patients | Blood sample and skin biopsy for assessment of IL35 by ELISA |
| |
| Normal healthy controls | Blood sample and skin biopsy for assessment of IL35 levels by ELISA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Skin biopsy | Diagnostic Test | biochemical assessment for measurement IL35 by ELISA (Enzyme linked immunosorbent assay) technique in tissue and serum samples of all thirty patients and healthy controls. |
| Measure | Description | Time Frame |
|---|---|---|
| To assess and compare tissue and serum levels of interleukin 35 (IL -35) in mycosis fungoides patients and normal controls. | To assess and compare tissue and serum levels of interleukin 35 (IL -35) in mycosis fungoides patients and normal controls. | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Correlating tissue and serum levels of IL-35 in mycosis fungoides patients with patients age, sex, duration, extent and stage of the disease. L | Correlating tissue and serum levels of IL-35 in mycosis fungoides patients with patients age, sex, duration, extent and stage of the disease. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
Subjects with history of solid or hematological malignancy as leukemia
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Patients with mycosis fungoides. Subjects attending plastic surgery units for abdominoplasty will be enrolled as controls.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sally Doss, MD | Contact | 01223283288 | Sallydoss@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Maha Fathy Elmasry, MD | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Recruiting | Giza | Egypt |
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| ID | Term |
|---|---|
| D009182 | Mycosis Fungoides |
| ID | Term |
|---|---|
| D016410 | Lymphoma, T-Cell, Cutaneous |
| D016399 | Lymphoma, T-Cell |
| D008228 | Lymphoma, Non-Hodgkin |
| D008223 | Lymphoma |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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|
| D009370 |
| Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |