Effects of GLP-1 Agonists on Gastric Volume

Ultrasound Assessment of Preoperative Gastric Volume in Fasted, Diabetic Surgical Patients: A Prospective Observational Cohort Study on the Effects of GLP-1 Agonists on Gastric Emptying

This study will enroll patients ages 18 and over who have a diagnosis of diabetes, are undergoing an elective surgery under general anesthesia and 1) are taking a GLP-1 receptor agonist medication, or 2) not taking a GLP-1 receptor agonist medication. The patients will have a gastric ultrasound prior to surgery to measure any retained gastric contents. The primary goal is to assess the effect of subcutaneous injectable GLP-1 agonists on preoperative gastric volume in fasted, diabetic surgical patients.

Inclusion Criteria

• Age greater than or equal to 18 years old
• Diagnosed with diabetes (listed on medical record, Hgb A1C greater than or equal to 6.5%, fasting blood glucose greater than or equal to 126mg/dL, and/or on medical treatment for diabetes)
• One of the following groups:
• Taking a GLP-1 Medication
• Not taking a GLP-1 Medication
• ASA Physical Classification Status 1-3
• Scheduled for elective surgery under general anesthesia
• Appropriately fasted per ASA Fasting Guidelines 201712

Exclusion Criteria

• BMI greater than 40
• Previous gastric/esophageal surgery
• Abnormal gastric anatomy
• Pregnancy
• Inability or unwillingness of subject to give informed consent
• Non-English Speaking