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At present, there is no relevant research focusing on children's acquisition of novel coronavirus antibodies through maternal passive transmission. Therefore, this study assessed the changes of maternal passive transmission of COVID-19 antibodies by monitoring the specific antibodies of COVID-19 in young children; This will lay a foundation for further exploring the risk of COVID-19 infection in children and formulating immune prevention strategies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group 1 | Mother not vaccinated with COVID-19 vaccine |
| |
| Control group 2 | The mother was vaccinated with COVID-19 vaccine before pregnancy, and was not infected during pregnancy |
| |
| Control group 3 | The mother was vaccinated with COVID-19 vaccine before pregnancy, and was infected during pregnancy |
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| Experimental group | The mother was not vaccinated with COVID-19 vaccine before pregnancy, so she was infected during pregnancy |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sars-cov-2 vaccine or infection | Biological | Whether to vaccinate COVID-19 vaccine, or infect with sars-cov-2 |
|
| Measure | Description | Time Frame |
|---|---|---|
| SARS-CoV-2 IgG | ELISA detection of SARS-CoV-2 IgG antibody levels | duration of time over which each participant could be 6-month to 12-month |
| SARS-CoV-2 neutralizing antibody | detection the level of SARS-CoV-2 neutralizing antibody | duration of time over which each participant could be 6-month to 12-month |
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Inclusion Criteria:
Exclusion Criteria:
Not willing to participate
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Samples of infants not infected with COVID-19 and not vaccinated with COVID-19 vaccine
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yuting Yang, Ms | Contact | 18990304808 | 412384223@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yuting Yang | Recruiting | Chongqing | Chongqing Municipality | 400014 | China |
Contact the project leader
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| ID | Term |
|---|---|
| D000086663 | COVID-19 Vaccines |
| ID | Term |
|---|---|
| D014765 | Viral Vaccines |
| D014612 | Vaccines |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
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