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| ID | Type | Description | Link |
|---|---|---|---|
| https://osf.io/36ukh | Registry Identifier | OSF |
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| Name | Class |
|---|---|
| University of Bonn | OTHER |
| Universitätsklinikum Hamburg-Eppendorf | OTHER |
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This study investigates the short-term effects of the MindEase app on anxiety levels.
Anxiety is a common symptom in the world's population (Whiteford et al., 2013). It occurs as a symptom within other mental disorders and as a disorder in itself (American Psychiatric Association, 2013).
There are several ways of dealing with anxiety, from short guidance for coping on a symptom level to professional health. (Emmelkamp & Ehring, 2014). Many people suffering from anxiety below a threshold indicating need for professional therapy may profit from strategies to calm down. (Helmchen & Linden, 2000). Among the strategies that are effective, there are guided interventions that people can use via a web-based interface on a computer or smartphone (Taylor et al., 2021). While it is known for most interventions that they are helpful, it is often unclear if they work also in web-based environments (Baumel et al., 2020). This is because most research regarding the topic investigates the effectiveness of mental-health apps as a whole, while research of specific interventions is missing (Domhardt et al., 2019). However, to develop effective apps, it is crucial to identify which specific interventions are most efficient in a web-based setting. (Domhardt et al., 2019; Firth et al., 2017). Therefore we want to identify interventions working effectively in an online format.
Mind Ease is an app that offers different established interventions within one framework to their users when they feel anxious. This framework makes the different interventions comparable to each other. For this reason, we will test the interventions that are used in the Mind Ease-app.
In a first study we will correlate the Mind Ease 3-sliders-score with the state-trait- anxiety-Inventory (SAI). In a second study we will measure participants'; acute anxiety (with the 3-sliders- score) before and after they performed a 10 minutes web-based cognitive or mindfulness-associated intervention. We will compare the anticipated reduction in anxiety to the reduction measured in participants in a control group.
Prospectively registered here: https://osf.io/36ukh
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| mindful breathing | Experimental |
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| deep breathing | Experimental |
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| cognitive therapy | Experimental |
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| dare response | Experimental |
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| defusion | Experimental |
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| in flow with fear | Experimental |
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| gratitude practice | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intervention with this name in MindEase app | Other | MindEase is an app which provides interventions against anxiety. The interventions are based on mindfulness, acceptance and commitment therapy, and cognitive behavioural therapy. |
| Measure | Description | Time Frame |
|---|---|---|
| change in anxiety score | sum of three slider questions on emotional state (3-sliders-score) | immediately before and immediately after the intervention |
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Inclusion Criteria:
Exclusion Criteria:
-
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jan M Brauner, MD | Contact | 00491779106783 | jan.brauner@eng.ox.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Jan M Brauner, MD | University of Oxford | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Oxford | Recruiting | Oxford | Oxfordshire | OX1 3QG | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40225732 | Derived | Sandkuhler JF, Kahl F, Sadurska MZ, Brietbart P, Greenberg S, Brauner J. The Immediate Impact of App-Based Psychotherapeutic Exercises on Anxiety: An RCT. Depress Anxiety. 2025 Apr 2;2025:5586831. doi: 10.1155/da/5586831. eCollection 2025. |
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Anonymous participant data will be accessible to anyone upon request.
Immediately after publication. No end date.
Anyone who wishes to access the data.
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| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D000544 | Alzheimer Disease |
| D003863 | Depression |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D008722 | Methods |
| ID | Term |
|---|---|
| D008919 | Investigative Techniques |
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Participants will be randomly assigned to an intervention or control condition.
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Participants are not told whether they are in an intervention or control condition. The app is both the care provider and the outcomes assessor. The investigator will be blinded while analysing the data.
| guided mindfulness | Experimental |
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| muscle relaxation | Experimental |
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| reframe your fears | Experimental |
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| calming visualization | Experimental |
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| reflective writing | Experimental |
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| reading about anxiety | Placebo Comparator |
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| do what you would usually do | No Intervention |
| reading about anxiety | Other | Participants are given an educational text to read about anxiety. |
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| D009422 |
| Nervous System Diseases |
| D024801 | Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |