Non-operative management (NOM) with antibiotics may be a safe alternative to surgery for uncomplicated appendicitis, but preoperative differentiation between uncomplicated and complicated appendicitis is challenging. The study aimed to develop a clinical-radiomics nomogram to distinguish uncomplicated from complicated appendicitis.

Inclusion Criteria:

• Pathologically diagnosed as acute appendicitis after appendectomy between January 2021 and December 2022.

Exclusion Criteria:

• age less than 18 years (no upper age limit);
• without CT examination within a week before surgery;
• difficult to outline the contours of the appendix due to inflammatory exudate;
• lack of clinical information.

All adults with pathologically diagnosed as acute appendicitis after appendectomy