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The current gold standard for severe mitral regurgitation is mitral valve plasty (PLM). The surgery allows the repair of the mitral valve, therefore without the need for mitral valve replacement (SVM), which involves the implantation of a biological prosthesis or a mechanical prosthesis.
However, PLM has a rate of failure, between 1-4% per year in degenerative mitral pathologies. As a result, patients with PLM failure and severe residual regurgitation are increasingly presenting in recent years.
Generally these patients are re-operated to replace the mitral valve. Our aim is to investigate the differences in re-operation involving mitral valve replacement or re-repair in patients who underwent mitral valve re-operation (re-repair or replacement) in our center between 2003 and 2017.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Re-PLM | Patient in which a new mitral valve repair is performed to treat failed mitral valve repair |
| |
| Re-SVM | Patient in which a mitral valve replacement is performed to treat failed mitral valve repair |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mitral valve repair (PLM) | Procedure | A mitral valve plasty is performed to treat mitral regurgitation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Survival after reintervention | Time of survival after reintervention for failed mitral valve repair | through study completion, a minimum of 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Risk factors for reintervention | Identification of predictors of reintervention after mitral valve repair | through study completion, a minimum of 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with a failure of mitral valve repair. The patients are divided in 2 groups depending on type of reintervention: a new mitral valve repair (PLM) or mitral valve replacement (SVM)
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Ospedale San Raffaele - Cardiac Surgery Department | Milan | 20132 | Italy |
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| ID | Term |
|---|---|
| C069141 | phospholemman |
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| Mitral valve replacement | Procedure | A mitral valve replacement with a prosthesis is performed to treat mitral regurgitation |
|