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The Australian Hepatitis and risk survey in prisons (AusHep) is a national prison-based blood-borne virus (BBV) surveillance study. This biobehavioural survey involves point-of-care testing for hepatitis C (HCV) antibodies and RNA (if antibody positive), hepatitis B surface antigens, hepatitis B surface antibodies, and HIV surface antibodies, and an interview-style survey on prior testing and treatment history and engagement in risk behaviours. The study will recruit approximately 2400 prisoner participants from 25 representative prisons across Australia, annually.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Persons in custody in Australia | Representative sample of 2400 people in prison from 25 representative prisons in Australia will participate in a biobehavioural survey involving point-of-care testing for HCV antibodies and RNA (if antibody positive), HBV surface antigens and antibodies, and HIV antibodies, and an interview-style survey. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Point-of-care hepatitis C antibody test | Diagnostic Test | Qualitative point-of-care test for hepatitis C antibodies (saliva sample) |
|
| Measure | Description | Time Frame |
|---|---|---|
| The prevalence of HCV in Australian prisons | This is estiamted by perfroming the HCV antibody test and HCV RNA viral load test on a representative prison population. | 1 Year |
| The prevalance of HBV in Australian prisons | This is estimated by performing the HBV surface antigen test on a respresentative prison population | 1 year |
| The prevalance of HIV in Australian prisons | This is estimated by performing the HIV antibody test on a respresentative prison population. | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| The proportion of individuals who are engaged in each step of HBV and HCV care cascades | This is estimated by conducting the bio-behavioural survey. | 1 Year |
| The prevalence of risk behaviours and harm reduction access |
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Inclusion Criteria:
Exclusion Criteria:
Individuals who are unable or unwilling to provide consent or abide by the requirements of the study, as assessed by the trained nurses. Some individuals may be considered unable to provide consent or abide by the requirements of the study if they are:
Those excluded from participating in the study will be referred to the local prison clinic service for standard of care.
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Participants will be recruited from the selected correctional centre(s) in each jurisdiction. All prisoners, including remandees and sentenced prisoners at the selected site(s) will be randomly selected to participate.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andrew Lloyd | Contact | 02 9385 2534 | a.lloyd@unsw.edu.au | |
| Yumi Sheehan | Contact | 02 9385 0375 | ysheehan@kirby.unsw.edu.au |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alexander Maconochie Centre | Not yet recruiting | Hume | Australian Capital Territory | 2620 | Australia | |
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| Point-of-care hepatitis C RNA test | Diagnostic Test | Hepatitis C Viral Load point-of-care test (fingerstick wholeblood sample) |
|
|
| Point-of-care hepatitis B surface antibody test | Diagnostic Test | Qualitative hepatitis B surface antibody point-of-care test (fingerstick wholeblood sample) |
|
|
| Point-of-care hepatitis B surface antigen test | Diagnostic Test | Qualitative hepatitis B surface antigen point-of-care test (fingerstick wholeblood sample) |
|
|
| Point-of-care HIV antibody test | Diagnostic Test | Qualitative HIV antibody point-of-care test (saliva sample) |
|
|
| Interview-style survey | Behavioral | Interview-style survey regarding demographics, risk behaviours, BBV testing and treatment history, and point-of-care testing acceptability |
|
The risk behavrious and harm reduction measures include injecting and non-injecting drug use, high risk injecting practices, sexual risk behaviours, tattooing; and bleach or opioid substitution therapy (OST) uptake. This is estimated by conducting the bio-behavioural survey.
| 1 Year |
| The factors associated with HCV and HBV infection investigated by the bio-behavioural survey. | 1 Year |
| The factors associated with engaging in each step of HCV and HBV care cascades and HBV vaccination investigated by the bio-behavioural survey. | 1 Year |
| Bathurst Correctional Complex |
| Completed |
| Bathurst |
| New South Wales |
| 2795 |
| Australia |
| John Morony Correctional Complex | Completed | Berkshire Park | New South Wales | 2756 | Australia |
| Cessnock Correctional Centre | Completed | Cessnock | New South Wales | 2325 | Australia |
| Mid North Coast Correctional Centre | Completed | Kempsey | New South Wales | 2440 | Australia |
| South Coast Correctional Centre | Completed | Nowra | New South Wales | 2541 | Australia |
| Silverwater Women's Correctional Centre | Completed | Silverwater | New South Wales | 2128 | Australia |
| Wellington Correctional Centre | Completed | Wuuluman | New South Wales | 2820 | Australia |
| Alice Springs Correctional Centre | Not yet recruiting | Alice Springs | Northern Territory | 0872 | Australia |
| Darwin Correctional Centre | Not yet recruiting | Howard Springs | Northern Territory | 0828 | Australia |
| Borallon Training and Correctional Centre | Recruiting | Ironbark | Queensland | 4306 | Australia |
| Brisbane Women's Correctional Centre | Completed | Ironbark | Queensland | 4306 | Australia |
| Wolston Correctional Centre | Completed | Ironbark | Queensland | 4306 | Australia |
| Townsville Correctional Centre | Completed | Townsville | Queensland | 4811 | Australia |
| Mobilong Prison | Completed | Murray Bridge | South Australia | 5253 | Australia |
| Adelaide Women's Prison | Completed | Northfield | South Australia | 5085 | Australia |
| Yatala Labour Prison | Completed | Northfield | South Australia | 5085 | Australia |
| Mary Hutchinson Women's Prison | Completed | Risdon Vale | Tasmania | 7016 | Australia |
| Risdon Maximum Prison | Completed | Risdon Vale | Tasmania | 7016 | Australia |
| Ron Barwick Minimum Security Prison | Completed | Risdon Vale | Tasmania | 7016 | Australia |
| Bunbury Regional Prison | Not yet recruiting | Bunbury | Western Australia | 6230 | Australia |
| Casuarina Prison | Not yet recruiting | Casuarina | Western Australia | 6167 | Australia |
| Roebourne Regional Prison | Not yet recruiting | Roebourne | Western Australia | 6718 | Australia |
| Bandyup Women's Prison | Not yet recruiting | West Swan | Western Australia | 6055 | Australia |
| ID | Term |
|---|---|
| D006526 | Hepatitis C |
| D006509 | Hepatitis B |
| D015658 | HIV Infections |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D006525 | Hepatitis, Viral, Human |
| D014777 | Virus Diseases |
| D018178 | Flaviviridae Infections |
| D012327 | RNA Virus Infections |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D018347 | Hepadnaviridae Infections |
| D004266 | DNA Virus Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |
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