Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study
Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study
This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.
The study hypothesis is that a low muscle mass at ICU admission, measured at the level of L3 on CT scans performed for clinical routine, and its change over the ICU stay predict the prognosis of the patient, especially the 30-day mortality, that it may at least be partly counteracted by nutritional support and that it is related with higher ICU and hospital costs.
The objectives of this retrospective study are to determine:
Inclusion Criteria:
Adults ≥ 18 yrs, hospitalized in the ICU of the HUG between January 1st 2010 and December 31st 2022 and Abdominal, or thoraco-abdominal CT scan measured 48 hours before to 96 hours after ICU admission in the HUG
Identical as for the associations of baseline body composition with clinical outcomes and At least one additional CT performed during the hospital stay
Exclusion Criteria:
CT scans of low quality or CT scans performed outside of the HUG or Presence of a documented refusal
Additionnally: oral nutrition, because we cannot assess the quantity and composition of oral intakes retrospectively