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Graftless sinus lift with simultaneous implant placement is one of the new techniques, this new technique is presented based on the physiology of intrasinus bone repair.
Schneiderian membrane is known to have an osteogenic nature, now blood clot can be considered autologous osteogenic graft material, to which osteoprogenitors can migrate, differentiate, and regenerate bone.
The aim of this study is to evaluate the effectiveness of using Fibrin glue versus Titanium platelet rich fibrin (T-PRF) as a sole filling material in lateral sinus lifting using with simultaneous implant placement in comparison to a negative control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study group 1 | Experimental |
| |
| Study group 2 | Experimental |
| |
| Control group | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fibrin Glue | Other | Blood samples were collected from the antecubital vein of the right or left arm of the patient and drawn into sterile Titanium tubes immediately. The tubes were then centrifuged for 12 minutes at 2800 rpm and room temperature |
| Measure | Description | Time Frame |
|---|---|---|
| change in implant stability | implant stability will be measures using Ostell device. | Baseline and 6 months |
| change in bone density | bone density will be measured using CBCT | Baseline and 6 months |
| change in vertical bone height | vertical bone height will be measured using CBCT | Baseline and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| change in pain intensity | This will be assessed using a 10-point Visual Analogue Scale (VAS) in the 1st week postoperatively. (0-1= None, 2-4= Mild, 5-7= Moderate, 8-10= Severe) | Through 1 week postopertaive |
| Change in edema score |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt | Alexandria | Azarita | 00203 | Egypt |
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| ID | Term |
|---|---|
| D015718 | Fibrin Tissue Adhesive |
| ID | Term |
|---|---|
| D005337 | Fibrin |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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| T-PRF | Other | The contents of the two containers (human fibrinogen, human thrombin) will be mixed with distilled water and then aspirated by two syringes after that, the two solutions will be mixed together and injected into the empty compartment around the dental implant under the sinus mucosal lining using auto mixing applicator. |
|
| Negative control | Other | this group will not receive any material. |
|
The score will be as follows:
| Through 1 week postopertaive |