Gastric Volume After Ingestion of Carbohydrate Drink vs Water in Obese Volunteers

Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obese Volunteers: A Randomized Crossover Study

This randomized crossover study compares gastric residual volume after ingestion of carbohydrate drinks and water in obese volunteers. The main question[s] it aims to answer are:

• Is it safe for obese patients to shorten their fasting by allowing preoperative drinks?
• How long is the gastric emptying time in obese patients? Participants also will be evaluated the level of thirst/hungry and blood sugar.

Inclusion Criteria:

• Healthy volunteers
• Age 18 - 65 years old
• BMI ≥ 30 kg/m2
• NPO for at least 6 hours before the study

Exclusion Criteria:

• Diabetes Mellitus
• Chronic kidney disease or End-stage renal disease
• Use of any medication that affects gastric secretion or emptying (Histamine 2 receptor antagonist eg. Ranitidine/Proton pump inhibitor eg. Omeprazole/Acid neutralization eg. Aluminium hydroxide/Prokinetic eg. Domperidone) within the past 24 hours
• Gastroesophageal reflux disease
• Pregnancy
• History of upper gastrointestinal surgery
• In diet program or use appetite suppressant drug (eg. Liraglutide, Naltrexone, Phentermine, Diethylpropion) within the past 24 hours