Impact of Black Seed Oil on Hemodialysis Patients

Evaluation of the Impact of Black Seed Oil on Hemodialysis Patients

The aim of the study is to evaluate the effect of black seed oil on endothelial dysfunction, oxidative stress and quality of life in hemodialysis patients.

Evaluation of the effect of black seed oil in hemodialysis patients via:

• Evaluation of serum Endothelin-1 levels
• Evaluation of serum Malondialdehyde (MDA) levels
• Evaluation of serum Total Antioxidant Capacity (TAC) levels
• Evaluation of Quality of Life (QOL)
• Evaluation of fatigue scale

Inclusion Criteria:

• Age ≥ 20 years old
• Three to four times per week hemodialysis
• Being on hemodialysis for at least 6 months
• Ability and willingness to cooperate in the study

Exclusion Criteria:

• Pregnancy or lactation
• Cigarette smoking or substance/alcohol abuse
• Having active infectious diseases
• Receiving steroidal or nonsteroidal anti-inflammatory drugs
• Using Nigella sativa oil regularly
• Changes in treatment methods (dialysis) or medications during the supplementation