The Effects of Bolus, Intermittent and Continuous Enteral Feeding on Blood Glucose and Feeding Intolerance in ICU Patients With Sepsis

The Comparison of Effects of Bolus, Intermittent (Nocturnal Pause) and Continuous Enteral Feeding Methods on Blood Glucose and Feeding Intolerance in ICU Patients With Sepsis, Prospective, Randomized, Controlled Study

Comparison of the effects of bolus, intermittent and continuous enteral feeding techniques on plasma glucose level and enteral feeding intolerance in adult intensive care unit patients with sepsis.

in this prospective, controlled trial the main aim is to evaluate the effects of bolus, intermittent and continuous enteral feeding techniques on plasma glucose level in intensive care patients with sepsis diagnosis and to determine whether they are superior to each other in providing norma-glycemia. The secondary aim is to determine the effect of these 3 different enteral feeding techniques on enteral feeding intolerance.

Inclusion Criteria:

• Hospitalized in ICU for more than 3 days
• Ages between 18-70 years
• APACHI II is in the range of 8-25
• BMI in the range of 18.5-30
• Able to receive enteral nutrition from N/G
• Intubated on ventilator support
• No previous diagnosis of Diabetes Mellitus,
• Those who have not had Gastro intestinal System surgery in the last 6 months
• Patients not receiving inotropic support
• not receiving hemodiafiltration
• No history of allergy to the food used
• Patients with a focus of infection and/or culture-positive patients diagnosed with sepsis according to Q SOFA (cultures were taken from all patients)

Exclusion Criteria:

• patient's death during the study
• Taking more than 40 mg of IV steroids daily
• Increased baseline APACHI II score
• Development of the patient's need for inotropes
• Elimination of inclusion criteria
• negative culture