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The goal of this observational study is to learn about the respiratory system in post-COVID syndrome. The main question aims to answer:
how the post-COVID syndrome alters the lung function Participants will be asked to perform lung function tests. Researchers will compare post-COVID group to matched control healthy individuals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-COVID | Patients with COVID-19 infections. |
| |
| Control | Patients without earlier diagnosis of COVID-19. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lung function test | Diagnostic Test | Spirometry to assess lung volumes, forced oscillations to measure respiratory mechanics, whole body plethysmography to assess static lung volumes and airway resistance, lung diffusion capacity measurements. |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory mechanics | Mechanical properties of the airways and respiratory tissues | 6-12 months after COVID-19 infections |
| Measure | Description | Time Frame |
|---|---|---|
| Spirometry | Forced expiratory lung volumes | 6-12 months after COVID-19 infections |
| Lung diffusion capacity | DLCO | 6-12 months after COVID-19 infections |
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Inclusion Criteria: COVID-19 infections in the post-COVID group. -
Exclusion Criteria:
-
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Adult patients after COVID-19 infection. In the control group, healthy volunteers.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Barna Babik | Contact | 0662545168 | babikbarna@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Barna Babik | Recruiting | Szeged | 6725 | Hungary |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38173937 | Derived | Palfi A, Balogh AL, Polonyi G, Schulcz D, Zollei E, Bari G, Fodor GH, Barath K, Somfay A, Petak F, Babik B. Post-COVID changes in lung function 6 months after veno-venous extracorporeal membrane oxygenation: a prospective observational clinical trial. Front Med (Lausanne). 2023 Dec 20;10:1288679. doi: 10.3389/fmed.2023.1288679. eCollection 2023. |
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| ID | Term |
|---|---|
| D000094024 | Post-Acute COVID-19 Syndrome |
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
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| ID | Term |
|---|---|
| D012129 | Respiratory Function Tests |
| ID | Term |
|---|---|
| D003948 | Diagnostic Techniques, Respiratory System |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| COVID infection | Biological | Verified COVID-19 infection. |
|
| Plethysmography | Measurement of functional residual capacity and airway resistance by using a whole body plethysmograph. | 6-12 months after COVID-19 infections |
| D007239 |
| Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D000094025 | Post-Infectious Disorders |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |