Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Sociedad Aragonesa de PatologÃa del Aparato Respiratorio | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
We hypothesized that diaphragm thickness is concerned in acute respiratory failure of COVID19 patients and its ultrasound measure at the begining of hospitalisation is a good predictor of poor outcome.
A prospective observational non intervention study is designed.
To answer our hypothesis we will perform diaphragm ultrasound in the first 24hr hospitalized COVID19 patients.
In the ultrasound exploration we will assess diaphragm movility and thickness. We will also assess other clinical, biochemistry and radiological variables. The main outcome we want to analyze is the destination on discharge: home, respiratory intermediate critical unit or exitus.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Diaphragmatic echography | Diagnostic Test | Diaphragmatic echography |
| Measure | Description | Time Frame |
|---|---|---|
| Early diaphragm ultrasound as a predictor factor for invasive and non invasive ventilation and death | This is the main outcome of our study given that it has a important clinical implications. If we confirm our hypothesis diaphragm ultrasound could prove to be a useful prognosis tool for COVID19 patients. | From date of inclusion until discharge date (lenght of hospitalization) |
| Measure | Description | Time Frame |
|---|---|---|
| Diaphragm thickness rate as a predictor factor for invasive and non invasive ventilation and death | Diaphragm strenght is directly related to thickness. The impact of COVID19 infection on this specific measure can predict patient evolution. | From date of inclusion until discharge date (lenght of hospitalization) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
People hospitalaised in pulmonology service
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Javier Lázaro Sierra | Zaragoza | 50001 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29703214 | Background | Marchioni A, Castaniere I, Tonelli R, Fantini R, Fontana M, Tabbi L, Viani A, Giaroni F, Ruggieri V, Cerri S, Clini E. Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation. Crit Care. 2018 Apr 27;22(1):109. doi: 10.1186/s13054-018-2033-x. | |
| 34830573 |
Not provided
Not provided
All investigators that can use these data are included as collaborators. Sharing that type of information is forbiden by our ethics comitee
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D000086382 | COVID-19 |
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| Diaphragm movility rate as a predictor factor for invasive and non invasive ventilation and death |
Diaphragm fatigability is directly related to movility. The impact of COVID19 infection on this specific measure can predict patient evolution. |
| From date of inclusion until discharge date (lenght of hospitalization) |
| Background |
| Pivetta E, Cara I, Paglietta G, Scategni V, Labarile G, Tizzani M, Porrino G, Locatelli S, Calzolari G, Morello F, Maule MM, Lupia E. Diaphragmatic Point-of-Care Ultrasound in COVID-19 Patients in the Emergency Department-A Proof-of-Concept Study. J Clin Med. 2021 Nov 14;10(22):5291. doi: 10.3390/jcm10225291. |
| 32457172 | Background | Schepens T, Fard S, Goligher EC. Assessing Diaphragmatic Function. Respir Care. 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. |
| 19017880 | Background | Boussuges A, Gole Y, Blanc P. Diaphragmatic motion studied by m-mode ultrasonography: methods, reproducibility, and normal values. Chest. 2009 Feb;135(2):391-400. doi: 10.1378/chest.08-1541. Epub 2008 Nov 18. |
| 38293643 | Derived | Lazaro Sierra J, Doz Arcas M, Claveria Marco P, Rosell Abos MT, Santolaria Lopez MA, Perez Gimenez L, Lanzuela Benedicto T, Zuil Martin M, Boldova Loscertales A, Garcia Saez S, Huertas Puyuelo A, Nieto Sanchez D, Carretero Garcia JA. Prognostic Value of Diaphragmatic Ultrasound in Patients Admitted for COVID-19 Pneumonia. Open Respir Arch. 2023 Dec 1;6(1):100290. doi: 10.1016/j.opresp.2023.100290. eCollection 2024 Jan-Mar. |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D012120 | Respiration Disorders |