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This randomized clinical trial will be conducted to investigate the efficacy of an innovative tooth cleaning agent extra virgin coconut oil with peppermint essential oil by oil pulling and toothbrushing with oil on reducing salivary Streptococcus mutans levels, tooth decay and plaque buildup versus on the counter toothpaste in high caries risk patients.
Everyday use of dental health care products has increased. Therefore, there is a legitimately increased interest of healthcare clinicians and consumers in substances added to the toothpaste with the intention to improve their performance and potential benefits and risks that may arise from it. As there are harmful products in the toothpaste for instance: (Fluoride, Sodium Lauryl Sulphate (SLS), Sodium Saccharin and Triclosan which is assumed that it because local reaction includes oral mucosa irritation and desquamation (stomatitis, glossitis, gingivitis, buccal mucositis), while systemic ones are allergic and acute or chronic toxic reactions. Rational Harmful products in the toothpaste for instance: (Fluoride, Sodium Lauryl Sulphate (SLS), Sodium Saccharin and Triclosan which is assumed that it because local reaction includes oral mucosa irritation and desquamation (stomatitis, glossitis, gingivitis, buccal mucositis), while systemic ones are allergic and acute or chronic toxic reactions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| virgin cold-pressed coconut oil with Peppermint essential oil | Experimental | Patients will be instructed to use one packet of the coco pull healthy blend of organic oil (virgin cold pressed coconut oil with Peppermint essential oil)and swish the oil in the mouth and pull it between teeth for 5 minutes then spit out the oil and brush their teeth with the oil for 2 minutes; such a regimen will be repeated twice daily for three months. |
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| The fluoride toothpaste (Colgate Total, | Active Comparator | Patients will be instructed to brush their teeth with the fluoride toothpaste (Colgat Total, 1450 ppm) for 2 minutes; such a regimen will be repeated two times daily for three months and use 10 ml of 0.12% chlorhexidine rinse for 1 min/day, 30 min after tooth brushing before going to bed. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AVIVA-PURE-CocoPull-Organic-made in USA | Other | virgin cold pressed coconut oil with Peppermint essential oil |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in the actual chance to avoid new lesion will be assessed | The Measuring test: Cariogram Model (KarabekiroÄŸlu et al 2017), The Measuring units : Percentage | T0: Baseline. T1: After one month. T2: After three months |
| Change in the bacterial count will be assessed | The measuring test:Colony forming unit, The measuring units : Cfu/mm2 (Prabakar et al., 2018) | T0: Baseline. T1: After one month. T2: After three months |
| Change in the salivary pH will be assessed | The measuring test: Digital pH meter, The measuring unit : Scoring system, (Sondos et al., 2019) (ordinal) | T0: Baseline. T1: After one month. T2: After three months |
| Change in the Plaque index will be assessed Löe-Silness (Loe 1963) | The measuring unit : Plaque index The oral hygiene and plaque amount will be estimated using a mirror and graduated periodontal probe in accordance with Silness and Löe plaque index, which assessed the amount of plaque in the cervical part of the tooth.The Plaque Index System
Löe-Silness (Loe 1963) (Sreenivasan et al.,2016), The Measuring units : Scoring system (ordinal) | T0: Baseline. T1: After one month. T2: After three months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the Bacterial virulence will be assessed | The Measuring test: Streptococcus mutans acidogenicity by Digital pH meter ,the maximum value is 7.2 less than it is bad value (Bedoya-Correa et al., 2021),the measuring units : Scoring system (ordinal) | T0: Baseline. T1: After one month. T2: After three months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry Cairo University | Cairo | Kasr El Ainy | 12613 | Egypt |
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Double-blind study