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| Name | Class |
|---|---|
| Laboratoire Interuniversitaire de Biologie de la Motricité | OTHER |
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The goal of this clinical trial is to precise the impact of menstrual cycle and physical activity on the hamstrings muscle function in healthy active women. The main question it aims to answer is : is there a moment of the menstrual cycle when the muscle is better able to recover from a strenuous exercise ? Three appointments will be conducted to evaluate the hamstring muscles at difference moments of the menstrual cycle. Echographic and maximal force production measures will be done.
Researchers will compare these results with a group taking oral contraceptives.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Menstrual cycle group | Experimental | Women who are not currently taking any form of hormonal contraception and who present a regular menstrual cycle. |
|
| Oral contraceptive group | Active Comparator | Women taking a second-generation oral contraceptive estrogen-progestogen pill. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hamstring muscles function assessment | Diagnostic Test | Ultrasound echographic evaluation of the hamstring muscles during stretching and voluntary contractions, before and after a strenuous physical activity. |
| Measure | Description | Time Frame |
|---|---|---|
| Hamstring muscles shear wave speed | Differences according to menstrual cycle phase in hamstring muscles shear wave speed, as measured by ultrasound elastography | Length of a menstrual cycle (around on 28 day average) |
| Measure | Description | Time Frame |
|---|---|---|
| Maximal voluntary force production | Differences according to menstrual cycle phase in maximal voluntary isometric hamstrings force production, as measured by an isokinetic dynamometer | Length of a menstrual cycle (around on 28 day average) |
| Hamstring muscles thickness |
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Inclusion Criteria:
physical exertion.
Menstrual cycle group:
hormonal variations related to the menstrual cycle, during the duration of the duration of the protocol and during the last 6 months after the participant's inclusion.
the participant. Mechanical contraception such as the diaphragm is permitted.
Oral contraceptive group:
- Taking oral contraception, 2nd generation monophasic pill estrogen-progestin pill (Optilova®, Optidril®, Leeloo®, Minidril®, Ludeal®, Zikiale®, Lovavulo®, Lovapharm®) for at least 6 months.
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Melanie PRUDENT, MD | Contact | 33472071862 | melanie.prudent@chu-lyon.fr | |
| Jeremie BOUVIER, MSc | Contact | jeremie.bouvier@univ-lyon1.fr |
| Name | Affiliation | Role |
|---|---|---|
| Alexandre Fouré, PhD | Université Claude Bernard Lyon 1 | Principal Investigator |
| Cyril Martin, PhD | Université Claude Bernard Lyon 1 | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratoire Interuniversitaire de Biologie de la Motricité | Recruiting | Villeurbanne | Rhône | 69622 | France |
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Differences according to menstrual cycle phase in hamstring muscles thickness, as measured by ultrasound echography. |
| Length of a menstrual cycle (around on 28 day average) |
| Hamstring muscles length of fascicles | Differences according to menstrual cycle phase in hamstring muscles fascicles' length, as measured by ultrasound echography. | Length of a menstrual cycle (around on 28 day average) |
| Hamstring muscles pennation angle | Differences according to menstrual cycle phase in hamstring muscles pennation angle, as measured by ultrasound echography. | Length of a menstrual cycle (around on 28 day average) |
| Hamstring muscles cross sectional area | Differences according to menstrual cycle phase in hamstring muscles cross sectional area, as measured by ultrasound echography. | Length of a menstrual cycle (around on 28 day average) |
| Hamstring tendons length | Differences according to menstrual cycle phase in hamstring tendons length, as measured by ultrasound echography. | Length of a menstrual cycle (around on 28 day average) |
| Maximal knee joint range of motion | Measure of the volunteer maximal knee range of motion, the maximum being defined by the volunteer as the greatest hip/leg angle reachable without feeling pain. The process is slowly conducted on an isokinetic ergometer by extending the knee joint (2°/s) until the volunteer reaches her maximal range of motion, at which point the movement is stopped and a security is placed. | Length of a menstrual cycle (around on 28 day average) |