The aim of the present study is to evaluate the adjunctive effect of glycine-powder air-polishing (GPAP) to full-mouth ultrasonic debridement (Fm-UD) in the treatment of peri-implant mucositis, and to determine the predictive role of implant and patient-level variables for disease resolution. Both treatments are described in the literature, but few studies are available on their comparison.

52 patients (132 implants) with peri-implant mucositis were included in this randomized parallel arm clinical study. Following baseline variables assessment, participants received Fm-UD. Implants allocated to the test group (n=64) were additionally treated with GPAP. Clinical outcomes were evaluated at 3 and 12 months following intervention. Complete and partial disease resolution were defined as absence of BoP (DR1) or <2 BoP+ sites (DR2), respectively.

Inclusion Criteria:

• age between 18 and 70 years old;
• presence of one implant loaded at least one year before;
• bleeding on probing and/or suppuration of the peri-implant mucosa;
• pain and/or tenderness of the peri-implant mucosa;
• good general health conditions.

Exclusion Criteria:

• radiographic bone loss ≥ 2mm;
• intake of anticoagulants, antiplatelet, antibiotic or cortisone drugs;
• inability to perform oral hygiene maneuvers.