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| ID | Type | Description | Link |
|---|---|---|---|
| P50MD017349 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| University of Chicago | OTHER |
| Rush University | OTHER |
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Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States. The investigators propose examining the feasibility and acceptability of the 12-week RN-CHeFRx (Real Nourishment and Cooking Healthy Food is Rx) intervention - grocery delivery, cooking classes, and nutrition education - for Black women with hypertension and obesity to improve nutritious eating habits and blood pressure control.
The objective of this study is to conduct the RN-CHeFRx (Real Nourishment and Cooking Healthy Food is Rx) for 12 weeks among Black women who are obese and hypertensive living Chicago. We propose to 1) Pilot the RN-CHEFRx intervention and measures that will be used to assess blood pressure, BMI status, and sodium intake with 20 Black women diagnosed with hypertension and BMI ≥ 30. We will assess the efficacy of the evaluation tools to be used in a future clinical trial at three-time points (baseline, 12 weeks, and 6 months); and 2) Assess the feasibility and acceptability of the RN-CHeFRx intervention using interviews, surveys, and documentary analysis. Findings from this study will inform a larger efficacy trial of RN-CHeFRx to improve dietary behaviors and blood pressure control among Black women with hypertension and obesity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Food is Medicine approach | Experimental | Groups of 10 will attend a 12 week intervention that includes cooking classes, grocery delivery and nutrition education. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RN-CHeFRx | Behavioral | The RN-CHeFRx trial to enhance dietary intake and blood pressure control in Black women with hypertension and obesity compared to usual care. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of participants who complete the 12 week intervention | Completion will be measured by class attendance | Up to 12 weeks |
| Number of participants recruited | Patients recruited, screened, eligible and consented to participate in the study | Up to 12 weeks |
| Number of participants who complete data collection visits | Completion measured by participants completing surveys, blood pressure measurements, and those who provide blood biospecimens | Baseline to 4 months |
| Acceptability of the intervention | Assessed via participant feedback | Up to 12 weeks |
| Change in mean blood pressures (mmHg) during intervention | Change will be measured by comparing blood pressures from baseline to 12 weeks | Baseline to 12 weeks |
| dietary intake during intervention | Dietary intake at baseline and 12 weeks | Baseline to 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in body weight during intervention | Change will be measured by comparing body weight obtained at baseline and 12 weeks | Up to 12 weeks |
| Change in body weight at 6 months | Change will be measured by comparing body weight (kg) obtained at 12 weeks and at 24 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Illinois Chicago | Chicago | Illinois | 60612 | United States |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 18, 2025 | |
| Unrelease | Jul 21, 2025 | |
| Release | Jul 21, 2025 | |
| Unrelease | Jul 22, 2025 | |
| Release | Jul 22, 2025 | |
| Reset | Aug 6, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 18, 2025 | Jul 21, 2025 | |||
| Jul 21, 2025 | Jul 22, 2025 |
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
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| 12 weeks to 24 weeks |
| Change in blood pressure at 6 months | Change will be measured by comparing systolic and diastolic blood pressure at 12 weeks to 24 weeks | 12 weeks to 24 weeks |
| Dietary intake during post-intervention | Dietary intake from 12 weeks to 24 weeks | 12 weeks to 24 weeks |
| Jul 22, 2025 | Aug 6, 2025 |
| D009748 |
| Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |