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| Name | Class |
|---|---|
| Technion, Israel Institute of Technology | OTHER |
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Alzheimer's disease dementia (AD) is a debilitating and prevalent neurodegenerative disease in older adults globally. Cognitive impairment, a hallmark of AD, is assessed through verbal tests that require high specialization, and while accepted as screening tools for AD, general practitioners seldom use them. AD can be diagnosed with expensive, invasive neuroimaging and blood tests, but these are usually conducted when cognitive functioning is already severely impaired. Thus, finding a novel, non-invasive tool to detect and differentiate mild cognitive impairment (MCI) and AD is a prime public health interest. Self-figure drawings (a projective tool in which individuals are asked to draw a picture of themselves), are easy to administer and have been shown to differentiate between healthy and cognitively impaired individuals, including AD. Convolutional Neural Network (CNN) (a type of deep neural network, applied to analyze visual imagery) has advanced to assess health conditions using art products. Therefore, the proposed study suggests utilizing CNN-based methods to develop and test an application tailored to differentiate between drawings of individuals with MCI, AD, and healthy controls (HC) using 4,000 self-figure drawings. This
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy controls | Adults aged 60 and above without cognitive impairment | ||
| Mild cognitive impairment | Adults 60 and above with mild cognitive impairment | ||
| Alzheimer's disease | Adults diagnosed with Alzheimer's disease |
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| Measure | Description | Time Frame |
|---|---|---|
| Cognition | The Montreal Cognitive Assessment (MoCA) is a 10-minute paper-based test that aims to detect MCI in older patients with symptomatology, suggesting impaired cognition. The MoCA is composed of 12 tasks to detect short-term memory, visuospatial ability, executive functioning, phonemic fluency, abstraction, attention, concentration, working memory, language, and orientation. | One day |
| Cognition for adults diagnosed with Alzheimer's disease | The Self-reported Cognitive Difficulties (CDS)75 is a 39-item questionnaire that requires participants or their caregivers in case of AD to rate how often they currently experience cognitive difficulties in everyday life using a 5-point scale (0 -"never" to 4 -"very often"). | One day |
| Self-figure drawing -Cognition | Self-figure drawing. Participants will be asked to draw themselves using a pencil on an A4-sized sheet of paper. | One day |
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Inclusion Criteria:
Exclusion Criteria:
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Adults aged 60 or above, who live in Israel.
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| Name | Affiliation | Role |
|---|---|---|
| Johanna Czamanski-Cohen, PhD | University of Haifa | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Haifa | Haifa | Israel |
This is an artificial intelligence study, thus there will not be a dataset available for sharing.
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| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D003072 | Cognition Disorders |