Comparison of Image Quality Between "Double Low Dose" Liver CT and Standard Liver CT

Comparison of Image Quality Between "Double Low Dose" Liver CT Using AI-based Iodine Boosting Reconstruction and Standard Contrast-enhanced Liver CT in Patients With Colorectal Cancer: Prospective, Randomized, Non-inferiority Trial

In patients with malignancies, contrast-enhanced abdominal CT (hereafter abdominal CT) plays an important role in detecting carcinoma recurrence and assessing treatment response. In this study, we aim to investigate whether such a "double low" dose CT is feasible in patients with liver metastases of colorectal cancer using a vendor-agnostic artificial intelligence-based noise reduction and contrast enhancement software.

Inclusion Criteria:

• colorectal cancer (CRC) patients
• on surveillance or monitoring for liver metastasis (of CRC)

Exclusion Criteria:

• any relative or absolute contra-indication of CECT
• diffuse infiltrative type of liver metastasis or on monitoring for too many liver lesions