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To examine how a low glycemic index diet (LGID) changes biochemical parameters, body measurements, and body image perception in obese individuals with insulin resistance. Obesity groups with insulin resistance who received a control diet (CD) and a LGID will be compared with each other in terms of biochemical parameters, body image perception and body measurements. In addition, each group will be compared with the start and end measurements over the same values.
The main purpose of this study is to determine the effect of LGID on body image perception, biochemical parameters and body measurements in obese individuals with insulin resistance.
Sub-objectives of the study;
Determination of the effect of LGID on fasting blood glucose, fasting insulin level and HOMA-IR levels compared to CD.
Determination of the effect of LGID on body weight, fat mass, muscle mass, body muscle ratio and body mass index (BMI) compared to CD.
Determination of the effect of LGID on body image perception status compared to CD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Diet | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low Glycemic Index Diet | Behavioral |
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| Measure | Description | Time Frame |
|---|---|---|
| Homeostatic Model Assessment for Insulin Resistance | Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index was obtained by the following formula: fasting glucose (mg/dl/18) x fasting insulin (U/mL)/22.5. A HOMA-IR index >2.5 is in favor of Insulin Resistance (IR). | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Cholesterol | Blood samples were collected after an overnight fast by using 10 mL plain tubes. Lipid profile was measured by using Cholesterol Kits and total cholesterol levels were measured using the sum of the LDL and HDL plus one-fifth of triglyceride levels. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Fasting plasma glucose | Fasting plasma glucose (FPG) levels were determined by taking a blood sample from participants who have fasted for at least 8 hours, Fasting glucose is between 75-95 mg/dL (4.2-5.3 mmol/L). | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Fasting insulin level | Fasting insulin is between 18-48 pmol/L. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body weight | Body weight was measured in kilograms. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body muscle ratio | Body muscle ratio as assessed by bioelectrical impedance analysis -- whole body composition was evaluated. |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of body image scale | The body image scale (BIS) includes 10 items, and was developed to briefly and comprehensively assess the affective (e.g., feeling self-conscious), behavioral (e.g., difficulty in looking at the naked body), and cognitive (e.g., satisfaction with appearance) aspects of body image in patients. It is a 4-point scale (0 = not at all and 3 = very much), and the final score is the sum of scores for 10 items, ranging from 0 to 30, with a lower score representing a better body image. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Üsküdar University | Istanbul | 34672 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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Different nutrition programs were applied to obese individuals divided into control and experimental groups. While the experimental group was given a healthy/balanced nutrition program containing carbohydrates and aimed to lose weight, a nutritional program that was balanced and aimed to lose weight but did not make any classification was applied to the control group. At the end of 8 weeks, biochemical parameters and scales were compared.
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prospective, two-arm randomized-controlled trial, Researchers who have no knowledge about group allocation and study's objectives, will collected the post-intervention data.
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| Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body muscle mass, kg | Body muscle mass as assessed by bioelectrical impedance analysis -- whole body composition was evaluated. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body mass index | Body mass index (BMI)=weight/(height)^2 | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body fat mass, kg | Body fat mass as assessed by bioelectrical impedance analysis -- whole body composition was evaluated. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Body fat ratio | Body fat ratio as assessed by bioelectrical impedance analysis -- whole body composition was evaluated. | Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| Changes within and between groups are evaluated on the start and last day of the intervention (day 120). |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |