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General objective: to improve care for haematological cancer survivors. This study will (i) Estimate the incidence of cancer survivor syndrome (CSS) in adult Egyptian patients with haematological neoplasms (HN). (ii) Asses the risk factors of CSS in patients with HN. (iii) Study the effect of CSS on quality of life in patients with HN. (iv) To explore coping strategies of patients with HN having CSS
According to the American Cancer Society the term cancer survivor refersto people who have no signs of cancer after finishing treatment, people receiving extended treatment over a longer period of time to control the cancer or reduce risk of its return, and people with advanced cancer. Most hematologic malignancies (HM) are incurable and typically follow unpredictable remitting-relapsing pathways associated with varying need for treatment, which may be distressing for patients. Distress symptoms and psychological disorders secondary to cancer have also been shown to have significant negative consequences for both the patient and the family.
Maladaptive coping and abnormal illness behavior have been associated with psychiatric conditions, with negative effects on adherence to treatment, health behavior, and quality of life (Grassi et al 2017). Moreover, an increased length of stay in the hospital and/or an increased time in rehabilitation have been found to be more common among patients showing psychiatric symptoms, especially depression, than those with normal adjustment to illness (Cordova et al 2017). Unfortunately, cancer-related distress is commonly underrecognized and subsequently undertreated especially for patients with HM in developing countries. Search in literature revealed several screening methods for the psychological consequences of cancer such as Distress Thermometer , Symptom related checklist questionnaire, Quality of life questionnaire, Coping strategies questionnaire. Also, guidelines for the management of psychological distress have been developed by several scientific cancer associations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Myloid group | Patients diagnosed as Multiple Myeloma, treated, and not in relapse |
| |
| Lymphoid group | Patients diagnosed as having lymphoma, treated, and not in relapse |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| questionnaire | Other | The symptom related checklist questionnaire, Quality of life questionnaire, Coping strategies questionnaire, Distress thermometer |
|
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of cancer survivor syndrome (CSS) | Estimate the incidence of cancer survivor syndrome (CSS) in adult Egyptian patients with hematological neoplasm neoplasms (HN) | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Asses the risk factors of CSS | Asses the risk factors of CSS in adult Egyptian patients with hematological neoplasm neoplasms (HN) | 2 years |
| Study the effect of CSS on quality of life | Study the effect of CSS on quality of life in adult Egyptian patients with hematological neoplasm neoplasms (HN) |
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Inclusion Criteria:
a. Inclusion criteria:
Exclusion Criteria:
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Cancer survivor syndrome patients with haematological malignancy divided into two groups:
Group 1: Myeloid neoplasms. Group 2: Lymphoid neoplasms in remission. The questionnaires will be collected from January 2023 to January 2025 in the Department of Hematology from Assiut University Hospital. This study will be approved from the Committee on Human Experimentation of Assiut University
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Roaa M Saleh, MD | Contact | 00201010617778 | roaasalh043@gmail.com | |
| Zain E Ahmed, MD, PhD | Contact | 01115596820 | Drzain73@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Safaa AA Khaled, MD, PhD | Professor, Department of Internal Medicine, Assiut University | Study Director |
| Zain E Ahmed, MD, PhD | Professor, Department of Internal Medicine, Assiut University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut University | Asyut | 71515 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10404478 | Background | Hann D, Winter K, Jacobsen P. Measurement of depressive symptoms in cancer patients: evaluation of the Center for Epidemiological Studies Depression Scale (CES-D). J Psychosom Res. 1999 May;46(5):437-43. doi: 10.1016/s0022-3999(99)00004-5. | |
| 23002383 | Background | Albrecht TA, Rosenzweig M. Management of Cancer Related Distress in Patients with a Hematological Malignancy. J Hosp Palliat Nurs. 2012 Oct 1;14(7):462-468. doi: 10.1097/NJH.0b013e318268d04e. |
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| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
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| 2 years |
| Exploring coping strategies | To explore coping strategies of adult Egyptian patients with hematological neoplasm neoplasms (HN) in CSS. | 2 years |
| Roaa M Saleh, MD | Resident Doctor, Department of Internal Medicine, Assiut University | Principal Investigator |
| 29259774 | Background | Grassi L, Spiegel D, Riba M. Advancing psychosocial care in cancer patients. F1000Res. 2017 Dec 4;6:2083. doi: 10.12688/f1000research.11902.1. eCollection 2017. |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |