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| ID | Type | Description | Link |
|---|---|---|---|
| 2022-A02135-38 | Other Identifier | ID-RCB number, ANSM |
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Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes clinical diagnosis difficult. It therefore seems important to improve the complementary examinations available to make the diagnosis more precise and to better study the effectiveness of the treatments implemented. The clinical examination and per-surgical findings of patients with deep pelvic endometriosis show a clear decrease in the mobility of the pelvic organs in relation to each other, but few studies have looked at this mobility, which could however have an implication in explaining the pathophysiology of the disease and the symptomatology of the patients, as well as in the detection of lesions preoperatively. The persistence of hypo-mobility could also help to understand treatment failures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients with pelvic endometriosis | Patients referred for suspected pelvic endometriosis, with pelvic endometriosis on initial MRI |
| |
| patients without pelvic endometriosis | Patients referred for suspected pelvic endometriosis but without endometriosis found on diagnostic MRI. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dynamic MRI Sequence | Other | Addition of a Dynamic MRI Sequence during the MRI examination performed in routine care |
|
| Measure | Description | Time Frame |
|---|---|---|
| the mean vertical displacement (in millimeters) measured on the anterior wall of the vagina between rest and maximum pushing force during dynamic MRI | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| the mean vertical displacement (in millimetres) measured on the cervix between rest and maximum thrust effort during dynamic MRI. | Baseline | |
| the mean vertical displacement (in millimetres) measured on the posterior wall of the vagina between rest and maximum pushing force during dynamic MRI. |
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Inclusion Criteria:
Exclusion Criteria:
Female, nulliparous
The population concerns patients referred to the Lille University Hospital for suspected pelvic endometriosis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chrystele RUBOD, MD,PhD | Contact | 0320445962 | chrystele.rubod@chru-lille.fr |
| Name | Affiliation | Role |
|---|---|---|
| Chrystele RUBOD, MD,PhD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de chirurgie gynécologique Hôpital Jeanne de Flandre - CHU de LILLE | Recruiting | Lille | France |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| D051346 | Mobility Limitation |
| D004194 | Disease |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| Baseline |
| the measurement of variation in mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort between the initial dynamic MRI of patients with | Baseline |
| the statistical association between the symptoms of patients with endometriosis and the mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort during dynamic MRI. | Initial symptoms are associated with initial dynamic MRI data and post therapeutic symptoms are associated with post-therapeutic dynamic MRI data. The symptoms of interest are dysmenorrhea, non-cyclic pelvic pain, dysuria, dychesia, transit disorders (diarrhea/constipation), and dyspareunia. | Baseline |
| D000091662 | Genital Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010335 | Pathologic Processes |