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The purpose the study is to successfully characterize the recovery phase of acute exacerbations of COPD in the outpatient setting using remotely captured physiologic data from wearable devices, to compare this with patient self-reported symptom data, to determine which physiologic variable(s) best correspond with AECOPD recovery, and to further document the feasibility, data quantity, data quality, and COPD outpatient usability experience with wearable devices.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COPD cohort | Patients with COPD currently experiencing and receiving treatment for an exacerbation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Biometric wearable devices | Device | Passive data collection using biometric wearable devices. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Daily symptom score | Validated AECOPD symptom score (EXACT PRO) will serve as the dependent (outcome) variable. | Daily for 21 days |
| Daily/nightly respiration | Respiratory rate (RR) will serve as the primary independent (predictor) variable, and RR variability will serve as a secondary independent (predictor) variable. | Daily for 21 days |
| Measure | Description | Time Frame |
|---|---|---|
| Daily/nightly heart rate and HR variability | HR and HRV will serve as secondary independent (predictor) variables. | Daily for 21 days |
| Daily/nightly peripheral body temperature | Temperature will serve as secondary independent (predictor) variables. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with COPD currently experiencing an exacerbation.
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| Name | Affiliation | Role |
|---|---|---|
| Bryan A. Ross, MD, FRCPC, MSc (Epi, Physiol) | Research Institute of the McGill University Health Centre (RI-MUHC) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada |
Due to data privacy regulations, individual participant data collected during this study is not publicly accessible. However, access to anonymized data may be granted upon evaluation by the trial management group. Additional documents will also be available upon inquiry. All requests should be directed to the corresponding author (BAR).
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| Daily for 21 days |
| Activity | Activity parameters (including calories, METS, step count, etc.) will serve as secondary independent (predictor) variables. | Daily for 21 days |
| Sleep metrics | Sleep metrics (including rem and non-rem stages of sleep; sleep duration, latency, efficiency, etc.) will serve as secondary independent (predictor) variables. | Daily (nightly) for 21 days. |
| Autonomic function/Stress | Metrics of stress/autonomic function (including electrodermal activity) will serve as secondary independent (predictor) variables. | Daily for 21 days |
| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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