Few previous studies have employed HA in the implant socket; instead, the majority have applied it topically to the area around dental implants after they have been placed. The application was done after suturing in these investigations. Therefore, the goal of the current study was to inject HA into the implant socket and onto the alveolar bone prior to implant insertion and suturing in order to preserve the HA for an extended period of time.

This study aims to use a visual analog scale (VAS) on the first, third, and tenth days following the surgical intervention to assess the efficacy of employing HA in dental implants in terms of pain reduction that may accompany dental implant surgery.

Inclusion Criteria:

• bilateral tooth loss with a sufficient amount of bone volume
• no general problems
• good oral health
• age between 20 and 60 years

Exclusion Criteria:

• the use of immunosuppressive drugs and corticosteroids for long periods
• the existence of serious systemic disorders
• contraindications for local anesthesia or oral surgery
• pregnant women and nursing mothers
• patients receiving chemotherapy or radiation
• alcoholics and heavy smokers.

Datasets and the underlying worksheets are available upon reasonable request from the corresponding author once the paper has been published.