Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project

Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project

The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or valvular heart disease (VHD) in community people aged 50-80 years who participate in the Utrecht Health Project.

The diagnosis strategy consists of a questionnaire with questions related to symptoms suggestive of CAD, AF or HF, a focused physical examination, laboratory testing, electrocardiography, and echocardiography.

Inclusion Criteria:

• Aged 50-80 years
• Being a participant of LRGP
• Having indicated in the LRGP informed consent to be interested in participating in further research.

Exclusion Criteria:

• Diagnosed with coronary artery disease and atrial fibrillation and heart failure.
• Undergoing major (cardiovascular) surgery, and/or revascularisation therapy and/or transplantation treatment within 3 months after enrolment.
• Not willing to give written informed consent for RED-LRGP.
• Not allowing incidental findings to be reported to him/herself or their own GP.