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The study will be a multicenter, hospital-based retrospective study. We plan to collect the clinical and laboratory data among all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then analyze the epidemiological and clinical characteristics of RSV infection, clarify the gene types of epidemics under 5 years old children after the outbreak in Wuhan, China.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neonatal |
| ||
| 1-3 months old |
| ||
| 3-6 months old |
| ||
| 6 months-1 year old |
| ||
| 1-2 years old |
| ||
| 2-5 years old |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observation | Other | clinical manifestation (body temperature, fever days before admission, cough, red throat/sore throat, runny nose, shortness of breath, wheezing, vomiting), physical signs (auscultation of lungs, X-ray results), length of stay, therapeutic measures (oxygen therapy, ICU admission, antibiotic therapy, etc.) |
| Measure | Description | Time Frame |
|---|---|---|
| number of patients with fever | number of patients with fever | at admission |
| number of patients with cough | number of patients with cough | at admission |
| number of patients with shortness of breath | number of patients with shortness of breath | at admission |
| number of patients with shortness of wheeze | number of patients with shortness of wheeze | at admission |
| number of patients with shortness of vomit | number of patients with shortness of vomit | at admission |
| number of patients with shortness of rale | number of patients with shortness of rale | at admission |
| number of patients with shortness of stridor | number of patients with shortness of stridor | at admission |
| age | age | at admission |
| gender |
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Inclusion Criteria:
â‘ Admission age <5 years old
â‘¡Clinical diagnosis of acute respiratory tract infections
Exclusion Criteria:
Hospital acquired ARTI
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all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then analyze the epidemiological and clinical characteristics of RSV infection, clarify the gene types of epidemics under 5 years old children after the outbreak in Wuhan, China
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| department of pediatrics, Tongji hospital, Tongji medical college, Huazhong University of Science and Technology | Wuhan | Hubei | 430030 | China |
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| ID | Term |
|---|---|
| D018357 | Respiratory Syncytial Virus Infections |
| ID | Term |
|---|---|
| D018186 | Pneumovirus Infections |
| D018184 | Paramyxoviridae Infections |
| D018701 | Mononegavirales Infections |
| D012327 | RNA Virus Infections |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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|
female/male
| at admission |
| number of patients with underlying disease | underlying disease include immune deficiency, CHD, BPD, BO, bronchiectasis and asthma and so on | at admission |
| Imaging examination results | X-Ray/CT | through study completion, an average of 1 year |
| length of hospital stay length of stay length of stay | length of hospital stay | through study completion, an average of 1 year |
| number of patients with treatment of antibiotic | number of patients with treatment of antibiotic | through study completion, an average of 1 year |
| number of patients with treatment of immunoglobulin | number of patients with treatment of immunoglobulin | through study completion, an average of 1 year |
| number of patients with treatment of glucocorticoids | number of patients with treatment of glucocorticoids | through study completion, an average of 1 year |
| number of patients with treatment of oxygen inhalation | number of patients with treatment of oxygen inhalation | through study completion, an average of 1 year |
| number of patients with treatment of ventilation | number of patients with treatment of ventilation | through study completion, an average of 1 year |
| direct medical cost | direct medical cost | through study completion, an average of 1 year |
| proportion of different virus genotype | virus genotype include A, B and C | through study completion, an average of 1 year |
| F protein gene sequence | F protein gene sequence | through study completion, an average of 1 year |
| number of patients infected with bacteria | number of patients infected with bacteria | through study completion, an average of 1 year |
| number of patients infected with virus | number of patients infected with virus | through study completion, an average of 1 year |
| number of patients infected with fungus | number of patients infected with fungus | through study completion, an average of 1 year |
| D014777 | Virus Diseases |
| D007239 | Infections |