Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia

Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia - a Phase 4 Clinical Trial

This study aims to compare ideal body weight- and total body weight-based dosage for remimazolam sedation of obese patients undergoing knee or hip arthroplasty under spinal anesthesia.

Inclusion Criteria:

• Patients scheduled for elective knee or hip arthroplasty under spinal anesthesia
• BMI>25
• American Society of Anesthesiologists (ASA) classification I, II, III

Exclusion Criteria:

• Patient refusal
• Contraindication for spinal anesthesia
• Contraindication for remimazolam infusion
• History of hypersensitivity to remimazolam
• History of chronic use of benzodiazepine or opioid
• Baseline MOAA/S score of 4 or lower
• Pregnancy