Guided Tissue Regeneration With a Periodontal Dressing

Guided Tissue Regeneration Combined With Periodontal Dressing: A Randomized Controlled Clinical Trial for the Treatment of Periodontal Defects

This randomized, controlled split-mouth study will include 24-40 patients. After GTR, a test and a control side will be selected by means of a computer-generated randomization list. Test sides will receive a periodontal dressing (Coepak") for 14 days and the control sides will receive no periodontal dressing. After 14 days the periodontal dressing will be removed and the pain experience will be recorded. After 6-9 months, the clinical periodontal parameters will be recorded.

Inclusion Criteria:

• Age between 18 and 75 years.

  • A minimum of 18 teeth, wisdom teeth excluded.
  • Previously untreated moderate chronic periodontitis (Armitage 1999) with radiographic evidence of generalized alveolar bone loss >30%.
  • Presence of at least one pocket with probing pocket depth (PPD) ≥6 mm per quadrant, which was BOP.
  • Presence of at least three teeth per quadrant.

Exclusion Criteria:

• Periodontal treatment in the last 3 years.

  • Antibiotic intake 6 months before • the screening visit.
  • Pregnancy. Systemic diseases with an impact on periodontal healing (e.g. Dia- betes).