Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial

Feasibility of an RCT to Investigate the Efficacy of Ice Plant Intensive Cream for the Prevention of Hand-foot Syndrome in Patients With Breast Cancer Receiving Therapy With Doxorubicin and/or Docetaxel: Pilot Randomized Controlled Trial

The present pilot study investigates the feasibility of a prospective larger confirmatory study on the efficacy of Dr. Hauschka Med Ice Plant Intensive Cream for the prevention of hand-foot syndrome in patients with breast carcinoma undergoing therapy with doxorubicin and / or docetaxel.

Inclusion Criteria:

• Breast cancer patients
• Therapy with Doxorubicin and/or Docetaxel
• Karnofsky performance status scale > 80
• Informed consent

Exclusion Criteria:

• Patients with previous skin disease and/or polyneuropathy
• Intolerance or allergic reaction on at least one ingredient of Ice Plant Intensive Cream
• Already receiving chemotherapy
• Usage of Ice Plant Intensive Cream before trial
• Severe physical or psychological illness due to which the patient is not able to participate in the study
• Lack of German language skills