The main objective of the study is to evaluate the improvement in quality of life after deep brain stimulation surgery with frameless technique by comparing the PDQ-39 scale score at baseline (before surgery) and one year after surgery.

Inclusion Criteria:

• diagnosis of idiopathic Parkinson's disease according to Movement Disorder Society (MDS) criteria;
• patients who are candidates for deep brain stimulation intervention, according to the international criteria of the "Core assessment program for surgical interventional therapies in Parkinson's disease" (CAPSIT-PD).

Exclusion Criteria:

- patients unable to give informed consent.

Patients affected by Parkinson's disease and candidates to intervention of deep brain stimulation.