Analysis of the Persistence, Reservoir and HIV Latency

APRIL Study: Analysis of the Persistence, Reservoir and HIV Latency

The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.

Inclusion Criteria:

• HIV-infection
• Adults (>18 years)
• Social insurance
• Informed consent

Exclusion Criteria:

• HIV-uninfected
• <18 years
• Lack of social insurance
• Lack or withdraw of consent