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| Name | Class |
|---|---|
| Fred Hutchinson Cancer Center | OTHER |
| Hackensack Meridian Health | OTHER |
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Screening for lung cancer has the potential for a profound public health benefit. Repeat annual screening is necessary for early detection of lung cancer. The investigators will test two interventions which include patient education and reminders to improve adherence to lung cancer screening.
Screening for lung cancer has the potential for a profound public health benefit.
Successful population-based screening requires continuous monitoring to adherence repeat screening in high risk adults to achieve similar results. Repeat annual screening is necessary for early detection of lung cancer. Baseline or first LDCT scans detect prevalent lung cancer, when subsequent screening detects new nodules. However, adherence to screening is low, ranging at 28-38% from centers nationally.
The investigators developed two novel, patient-centered interventions to address patient education and offering reminders for on-time screening. To address these goals, the specific aims are to: 1) Compare effectiveness of two multilevel interventions relative to usual care in improving (a) rates of adherence to lung cancer screening, (b) patient-centered outcomes; and (c) clinic outcomes; and 2) Determine the patient-, clinician-, and system-level factors that influence changes in adherence to inform lung cancer screening programs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient Video only | Experimental | About 3 weeks after the index LDCT, the study Medical Assistant (MA) will deliver a link to the Patient Voices Video, an educational video about lung cancer screening. |
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| Stepped Reminders only | Experimental | Prior to patient's next LDCT scan is due, MA begins Stepped Reminders intervention: MA pends LDCT orders to PCP to sign. MA sends reminders to patient when order is placed and follows up by phone if patient has not scheduled LDCT. |
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| Patient Video and Stepped Reminders | Experimental | See above. Those assigned to the Patient Video and Stepped Reminders will receive both interventions, as described above. |
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| Usual Care | No Intervention | Those assigned to the the Usual Care arm will continue to receive usual lung cancer screening care. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stepped Reminders | Other | Stepped Reminders, which directly reminds providers to order the next LDCT scan and then reminds patients they are due and prompts them to schedule LDCT with Radiology. |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of repeat annual lung cancer screening | Electronic health records will be searched for screening low dose CT (LDCT). | 9-15 months after index LDCT |
| Measure | Description | Time Frame |
|---|---|---|
| Knowledge of lung cancer screening | Knowledge of lung cancer screening eligibility, time to return and cost on patient reported outcomes survey. | 8 weeks after index LDCT |
| Attitudes and beliefs |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Karen Wernli, PhD | Kaiser Permanente | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaiser Permanente | Seattle | Washington | 98101 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41333381 | Derived | Vasavada A, Palazzo L, Luce C, Sanchez M, Triplette M, Ralston JD, Carter-Bawa L, Green BB, Gao H, Li CI, Anderson ML, Su YR, Rogers K, Wernli KJ. "It's coming whether we want it to or not": A qualitative exploration of older adults' comfort with and perceptions of technology and digital health. Res Sq [Preprint]. 2025 Nov 19:rs.3.rs-8001649. doi: 10.21203/rs.3.rs-8001649/v1. | |
| 40939933 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 8, 2026 |
| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D010353 | Patient Education as Topic |
| ID | Term |
|---|---|
| D006266 | Health Education |
| D011314 | Preventive Health Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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| Patient Education | Other | The Patient Voices Video is an educational video about lung cancer screening. |
|
The Lung Cancer Screening Health Belief Scale measures self-efficacy for lung cancer screening. The self-efficacy for lung cancer screening scale ranges from 9-36, with higher scores indicating lower self-efficacy.
| 8 weeks after index LDCT |
| Derived |
| Wernli KJ, Anderson ML, Palazzo L, Luce C, Bezman N, Chin M, Gao H, Ralston JD, Rogers K, Su YR, Triplette M, Carter-Bawa L, Vasavada A, Jordan M, West M, Boler S, Green BB. Effectiveness of Health Communication Intervention to Improve Knowledge on Timeliness to Return for Annual Lung Cancer Screening: The Larch Trial. Chest. 2026 Feb;169(2):550-561. doi: 10.1016/j.chest.2025.07.4111. Epub 2025 Sep 10. |
| 38467273 | Derived | Luce C, Palazzo L, Anderson ML, Carter-Bawa L, Gao H, Green BB, Ralston JD, Rogers K, Su YR, Tuzzio L, Triplette M, Wernli KJ. A pragmatic randomized clinical trial of multilevel interventions to improve adherence to lung cancer screening (The Larch Study): Study protocol. Contemp Clin Trials. 2024 May;140:107495. doi: 10.1016/j.cct.2024.107495. Epub 2024 Mar 11. |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |