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Abstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification.
Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.
Result:
Conclusion:
bstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification as determined by the American Academy of Periodontology and the European Federation of Periodontology (AAP-EFP) Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gingivitis | 0% interdental bone loss |
| |
| Stage 1 periodontitis | 0-15% interdental bone loss |
| |
| Stage 2 Periodontitis | 15-33% interdental bone loss |
| |
| Stage 3 Periodontitis | >33% interdental bone loss with potential for additional tooth loss |
| |
| Stage 4 Periodontitis | >%33 interdental bone loss with potantial for loss of dentition |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HbA1c, Vitamin D, Vitamin B12 | Diagnostic Test | Serum HbA1c, Vitamin D, Vitamin B12 values of the patients who applied for gingival treatment in the last 3 months from the date of application were found from the hospital archive and serum was not taken from the patients again for the study. |
| Measure | Description | Time Frame |
|---|---|---|
| HbA1c | serum Hemoglobin A1c value | t0:baseline |
| Vitamin D | serum Vitamin D value | t0 : baseline |
| Vitamin B12 | serum Vitamin B12 value | t0:baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients between the ages of 18-80, who applied to the clinic due to periodontal disease, and had serum HbA1c, vitamin D, vitamin B12 values in the hospital archive within 3 months from the date of clinical application.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nigde Omer Halisdemir University, Dentistry Faculty, Periodontology Department | Niğde | 06800 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29926952 | Background | Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018 Jun;89 Suppl 1:S159-S172. doi: 10.1002/JPER.18-0006. | |
| 39007836 | Derived | Bulut SO, Noyun D, Dirikan Ipci S, Cakar G. Serum vitamin D, hemoglobin A1c and vitamin B12 levels in patients with gingivitis and periodontitis stages. Biomark Med. 2024;18(9):449-457. doi: 10.1080/17520363.2024.2342236. Epub 2024 May 17. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |