The goal of this randomized clinical trial study is to compare safety profile undiluted intracameral moxifloxacin vs levofloxacin during cataract surgery. The main question it aims to answer is whether moxifloxacin and levofloxacin have similar safety profile.

Participant will be randomized into two treatment arms. All participant will receive standardized treatment before, during, and after surgery and will be followed up at one day, one week, and one month after surgery.

This study aims to observe the safety profile in patient receiving cataract surgery who receives moxifloxacin and levofloxacin intracamerally during the surgery. Safety profile defined as visual acuity, intraocular pressure, corneal endothelial cell density, central corneal thickness, anterior chamber reactions, and central macular thickness. Parameters are obtained before the surgery, 1 day, 1 week, and 1 month after surgery. Subjects are randomized to two treatment arms: (1) receiving undiluted moxifloxacin 0.1 cc during surgery; (2) receiving undiluted levofloxacin 0.1 cc during surgery.

Inclusion Criteria:

• Immature senile cataract in one or both eye
• Agree to be included and signed informed consent

Exclusion Criteria:

• Have a history of allergy to moxifloxacin or levofloxacin or any other antibiotics
• Other ocular comorbid such as uveitis, glaucoma, diabetic retinopathy, pseudoexfoliation, and endothelial disorders
• Ocular surgery prior to study
• Sign of infection or inflammation around the eye
• Cataract density more than grade 4 according to Lens Opacities Classification System (LOCS) III grading
• Corneal endothelial cell density < 1500 cell/ mm2
• Anterior chamber depth < 2.5 mm
• Diabetes mellitus type 2

Participant will be masked receiving treatment, post operative eye drops of both arms is the same. Subject allocation is blinded to investigator and outcomes assessor.