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The gaol of this randomized clinical trial was to compare the effect of self-etching primer bonding system and one step adhesive bonding system on the development of white spot lesions (WSLs) during fixed orthodontic therapy in comparison with the conventional 3 step bonding system.
All participants will be bonded with similar fixed orthodontic appliances using each type of adhesives for the assigned group. WSLs will be monitored during the orthodontic treatment
Objectives: The objective of this clinical trial was to compare the effect of self-etching primer bonding system and one step adhesive bonding system on the development of WSLs during fixed orthodontic therapy in comparison with the conventional 3 step bonding system.
Materials and Methods: Seventy five patients were randomly allocated into 3 groups (Group 1, conventional bonding system, n=25; Group 2, self-etch primer n=25; Group 3, primer mixed with the adhesive composite n=25). Quantitative light-induced fluorescence (QLF) was used to quantify WSL parameters. Images were captured and then analyzed before treatment; 2 months and 4 months after bond-up. Lesion area (Pixels), mean fluorescence loss (∆F) and the number of newly developed WSLs were compared within and between the 3 groups. The significance level was set at P ≤ 0.05.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Three-step adhesive | Active Comparator | The orthodontic appliances were bonded to the patients teeth using conventional 3 step adhesive (3Mâ„¢ Transbondâ„¢ XT, 3M Unitek, United States) |
|
| Self-etch primer adhesive | Experimental | The orthodontic appliances were bonded to the patients teeth using self-etch primer (3Mâ„¢ Transbondâ„¢ Plus, 3M Unitek, United States). |
|
| One-step adhesive system | Experimental | The orthodontic appliances were bonded to the patients teeth using one-step adhesive system (GC Ortho Connectâ„¢, GC Orthodontics, Germany) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adhesive bonding systems | Combination Product | Three different adhesive bonding systems were used; one system per group |
|
| Measure | Description | Time Frame |
|---|---|---|
| Average lesion fluorescence loss (ΔF%) | It reflects mineral loss from tooth surface (in percent) | 4 months |
| surface area of WSL | Area of mineral loss measured in pixels | 4 months |
| Incidence of WSL | Number of newly developed WSLs | 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum lesion fluorescence loss (ΔFMAX%) | It reflects the deepest area of the WSL (in percent) | 4 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Susan Al-Khateeb, PhD | Faculty of Dentistry/Jordan University of Science and Technology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Postgraduate Dental Teaching Clinics/JUST | Irbid | 22110 | Jordan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 6758594 | Background | Gorelick L, Geiger AM, Gwinnett AJ. Incidence of white spot formation after bonding and banding. Am J Orthod. 1982 Feb;81(2):93-8. doi: 10.1016/0002-9416(82)90032-x. | |
| 27476362 | Background | Mohammed RE, Abass S, Abubakr NH, Mohammed ZM. Comparing orthodontic bond failures of light-cured composite resin with chemical-cured composite resin: A 12-month clinical trial. Am J Orthod Dentofacial Orthop. 2016 Aug;150(2):290-4. doi: 10.1016/j.ajodo.2016.02.013. |
| Label | URL |
|---|---|
| Randomization App | View source |
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Data will be available upon request
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Three parallel groups
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The investigator was capturing the images (that were analyzed to measure the outcomes), while a research assistant was saving the images of the patients with coding system
| 13271655 | Background | BUONOCORE MG. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Dent Res. 1955 Dec;34(6):849-53. doi: 10.1177/00220345550340060801. No abstract available. |
| 8922502 | Background | Frazier MC, Southard TE, Doster PM. Prevention of enamel demineralization during orthodontic treatment: an in vitro study using pit and fissure sealants. Am J Orthod Dentofacial Orthop. 1996 Nov;110(5):459-65. doi: 10.1016/s0889-5406(96)70050-1. |
| 27007753 | Background | Miller CC, Burnside G, Higham SM, Flannigan NL. Quantitative Light-induced Fluorescence-Digital as an oral hygiene evaluation tool to assess plaque accumulation and enamel demineralization in orthodontics. Angle Orthod. 2016 Nov;86(6):991-997. doi: 10.2319/092415-648.1. Epub 2016 Mar 23. |
| 16448281 | Background | Bishara SE, Ajlouni R, Laffoon JF, Warren JJ. Comparison of shear bond strength of two self-etch primer/adhesive systems. Angle Orthod. 2006 Jan;76(1):123-6. doi: 10.1043/0003-3219(2006)076[0123:COSBSO]2.0.CO;2. |
| Background | Elkalza, A., Mostafa, D. (2018). 'Laboratory evaluation of shear bond strength of three different bonding systems for orthodontic brackets', Egyptian Orthodontic Journal, 53(June 2018), pp. 55-60. doi: 10.21608/eos.2018.77121 |
| 34202013 | Background | Choi A, Yoo KH, Yoon SY, Park BS, Kim IR, Kim YI. Anti-Microbial and Remineralizing Properties of Self-Adhesive Orthodontic Resin Containing Mesoporous Bioactive Glass. Materials (Basel). 2021 Jun 25;14(13):3550. doi: 10.3390/ma14133550. |
| 9743128 | Background | Bishara SE, Gordan VV, VonWald L, Olson ME. Effect of an acidic primer on shear bond strength of orthodontic brackets. Am J Orthod Dentofacial Orthop. 1998 Sep;114(3):243-7. doi: 10.1016/s0889-5406(98)70205-7. |
| 11395706 | Background | Bishara SE, VonWald L, Laffoon JF, Warren JJ. Effect of a self-etch primer/adhesive on the shear bond strength of orthodontic brackets. Am J Orthod Dentofacial Orthop. 2001 Jun;119(6):621-4. doi: 10.1067/mod.2001.113269. |
| 26061985 | Background | Montasser MA, El-Wassefy NA, Taha M. In vitro study of the potential protection of sound enamel against demineralization. Prog Orthod. 2015;16:12. doi: 10.1186/s40510-015-0080-2. Epub 2015 May 22. |
| 25391496 | Background | Paschos E, Rosenbeck KA, Huth KC, Rudzki I, Wichelhaus A, Kunzelmann KH. Evaluation of the effect of bracket-periphery treatment on prevention of enamel demineralization by consecutive muCT scans. Clin Oral Investig. 2015 Jul;19(6):1519-26. doi: 10.1007/s00784-014-1351-x. Epub 2014 Nov 14. |
| 14158464 | Background | SILNESS J, LOE H. PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION. Acta Odontol Scand. 1964 Feb;22:121-35. doi: 10.3109/00016356408993968. No abstract available. |
| 5237684 | Background | Loe H. The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol. 1967 Nov-Dec;38(6):Suppl:610-6. doi: 10.1902/jop.1967.38.6.610. No abstract available. |
| 32354432 | Background | Albhaisi Z, Al-Khateeb SN, Abu Alhaija ES. Enamel demineralization during clear aligner orthodontic treatment compared with fixed appliance therapy, evaluated with quantitative light-induced fluorescence: A randomized clinical trial. Am J Orthod Dentofacial Orthop. 2020 May;157(5):594-601. doi: 10.1016/j.ajodo.2020.01.004. |
| 24952017 | Background | Al-Khateeb SN, Tarazi SJ, Al Maaitah EF, Al-Batayneh OB, Abu Alhaija ES. Does acid etching enhance remineralisation of arrested white spot lesions? Eur Arch Paediatr Dent. 2014 Dec;15(6):413-9. doi: 10.1007/s40368-014-0131-2. Epub 2014 Jun 21. |
| 6573846 | Background | Houston WJ. The analysis of errors in orthodontic measurements. Am J Orthod. 1983 May;83(5):382-90. doi: 10.1016/0002-9416(83)90322-6. |
| 3466795 | Background | Artun J, Brobakken BO. Prevalence of carious white spots after orthodontic treatment with multibonded appliances. Eur J Orthod. 1986 Nov;8(4):229-34. doi: 10.1093/ejo/8.4.229. No abstract available. |
| 23289733 | Background | Julien KC, Buschang PH, Campbell PM. Prevalence of white spot lesion formation during orthodontic treatment. Angle Orthod. 2013 Jul;83(4):641-7. doi: 10.2319/071712-584.1. Epub 2013 Jan 4. |
| 26241805 | Background | Brown MD, Campbell PM, Schneiderman ED, Buschang PH. A practice-based evaluation of the prevalence and predisposing etiology of white spot lesions. Angle Orthod. 2016 Mar;86(2):181-6. doi: 10.2319/041515-249.1. Epub 2015 Aug 4. |
| 19409343 | Background | Paschos E, Kleinschrodt T, Clementino-Luedemann T, Huth KC, Hickel R, Kunzelmann KH, Rudzki-Janson I. Effect of different bonding agents on prevention of enamel demineralization around orthodontic brackets. Am J Orthod Dentofacial Orthop. 2009 May;135(5):603-12. doi: 10.1016/j.ajodo.2007.11.028. |
| 25158949 | Background | Visel D, Jacker T, Jost-Brinkmann PG, Prager TM. Demineralization adjacent to orthodontic brackets after application of conventional and self-etching primer systems. J Orofac Orthop. 2014 Sep;75(5):358-73. doi: 10.1007/s00056-014-0233-9. Epub 2014 Aug 28. |
| 31545075 | Background | Rasmussen MJ, Togrye C, Trojan TM, Tantbirojn D, Versluis A. Post-gel shrinkage, elastic modulus, and stress generated by orthodontic adhesives. Angle Orthod. 2020 Mar;90(2):278-284. doi: 10.2319/032719-233.1. Epub 2019 Sep 23. |
| 3164585 | Background | Ogaard B, Rolla G, Arends J. Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am J Orthod Dentofacial Orthop. 1988 Jul;94(1):68-73. doi: 10.1016/0889-5406(88)90453-2. |
| 15591733 | Background | Boersma JG, van der Veen MH, Lagerweij MD, Bokhout B, Prahl-Andersen B. Caries prevalence measured with QLF after treatment with fixed orthodontic appliances: influencing factors. Caries Res. 2005 Jan-Feb;39(1):41-7. doi: 10.1159/000081655. |
| 21208070 | Background | Tufekci E, Dixon JS, Gunsolley JC, Lindauer SJ. Prevalence of white spot lesions during orthodontic treatment with fixed appliances. Angle Orthod. 2011 Mar;81(2):206-10. doi: 10.2319/051710-262.1. |
| 19201328 | Background | Ghiz MA, Ngan P, Kao E, Martin C, Gunel E. Effects of sealant and self-etching primer on enamel decalcification. Part II: an in-vivo study. Am J Orthod Dentofacial Orthop. 2009 Feb;135(2):206-13. doi: 10.1016/j.ajodo.2007.02.060. |
| 2816842 | Background | Ogaard B. Prevalence of white spot lesions in 19-year-olds: a study on untreated and orthodontically treated persons 5 years after treatment. Am J Orthod Dentofacial Orthop. 1989 Nov;96(5):423-7. doi: 10.1016/0889-5406(89)90327-2. |
| 1298574 | Background | Donly KJ, Ruiz M. In vitro demineralization inhibition of enamel caries utilizing an unfilled resin. Clin Prev Dent. 1992 Nov-Dec;14(6):22-4. |
| 16448283 | Background | Cal-Neto JP, Miguel JA. Scanning electron microscopy evaluation of the bonding mechanism of a self-etching primer on enamel. Angle Orthod. 2006 Jan;76(1):132-6. doi: 10.1043/0003-3219(2006)076[0132:SEMEOT]2.0.CO;2. |