Effects of BFR Interventions in Healthy Individuals and Individuals With COPD

Effects of BFR Interventions on Muscle Function and Adaptations in Healthy Individuals and Individuals With COPD

The purpose of the study is to investigate the effect of different blood flow restriction (BFR) interventions on muscle function and adaptations both in healthy well-trained individuals and individuals diagnosed with COPD.

Inclusion criteria for participants with COPD group are:

• Diagnosis with COPD

Exclusion criteria participants in the COPD group are

• Having experienced an acute exacerbation of COPD within the last 6 weeks (Study A)
• Taking part in pulmonary rehabilitation within the last 3 months (Study A)
• Presenting with a history of thromboembolic event in the lower limbs.

Inclusion criteria for healthy participants are:

• Age between 18 and 40 years.
• Maximal oxygen uptake (VO2max) of >55 ml O2/kg/min for men and >50 ml O2/kg/min for women
• BMI of <26 and normal ECG and blood pressure.

Exclusion criteria for healthy participants are:

• Smoking
• chronic disease,
• Use of prescription medication
• Pain due to current or previous musculoskeletal injury
• Resistance training more than once per week in the 12 months leading up to the intervention.