Genetics of Appendix Cancer Study

Genetics of Appendix Cancer: The GAP Study

The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.

The Genetics of Appendix Cancer (GAP) Study aims to analyze hereditary factors, tumor characteristics and clinical features/outcomes among adults diagnosed with appendix cancer and their biological parents. Patients are recruited at any time after a diagnosis of appendix cancer and followed for up to 6 years after study enrollment. This cohort is enriched by robust biospecimens and data collections.

Inclusion Criteria:

GAP Social

• Known diagnosis of appendix cancer in the United States
• Mentally and physically able to consent and participate in the study

GAP Vanderbilt

• Known diagnosis of appendix cancer
• Diagnosed by and/or consulting with a physician/clinical provider participating in the GAP Study
• Mentally and physically able to consent and participate in the study

GAP Parent

• Biological parents (mother and/or father) of individuals actively participating in the GAP Study
• Residing in the United States
• Mentally and physically able to consent and participate in the study

Exclusion Criteria:

• Women pregnant at the time of consent
• Prisoners
• Unable to provide informed consent
• Unable to read, write, or complete questionnaires in English