To learn about the symptoms and changes our patients experience while receiving treatment for sinonasal or nasopharyngeal cancer

Objectives:

• To estimate the prevalence and severity of adverse and functional outcomes in survivors of benign and malignant paranasal sinus, nasopharynx and skull base tumors.
• To estimate the prevalence of health promotion behaviors during skull base tumor survivorship
• To identify possible mediators or predictors of survivorship outcomes and health behaviors in survivors of skull base tumors.
• To develop a database of demographic, clinicopathologic, recurrence, survival, functional and patient reported outcomes (PROS) for patients with benign and malignant paranasal sinus, nasopharyngeal and skull base tumors.
• To assess the utility and limitations of PROs in evaluating functional impairments and symptom burden in skull base patients.

Inclusion criteria:

1. Previously untreated patients with or suspected to have sinonasal malignancy or nasopharyngeal malignancy diagnosis based on either outside pathology report or MD Anderson pathology report.
2. Age ≥ 18 years
3. Plan to obtain the majority of treatment at MDACC including surgery and radiotherapy
4. Ability to understand and willingness to sign written informed consent

Exclusion criteria:

1. History of the previous solid or liquid malignancies, apart from skin cancers treated with local therapy.
2. Existing neurocognitive impairment that is not the result of sinonasal and nasopharyngeal cancers or is treatment.
3. Previous treatment for sinonasal or nasopharyngeal carcinomas, apart from biopsy.

M D Anderson Cancer Center