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Aim : The aim of present study was to evaluate BMAC/bovine graft utilization in Sinus membrane augmentation on bone quality and quantity. Methodology: sixteen patients suffering from atrophic posterior maxilla with sinus pneumatization were randomly divided into two equal groups: study group: the sinus membrane was elevated with BMAC/bovine graft whereas the control group recieved bovine graft only for sinus floor augmentation.
All patients will be evaluated at 1 week, 4 months to measure bone height and bone core biopsy for histological assessment at 4 months during implant placement.
Aim : The aim of present study was to evaluate BMAC/bovine graft utilization in Sinus membrane augmentation on bone height gain and quality of bone on histological assessment.
Methodology: sixteen patients suffering from atrophic posterior maxilla with sinus pneumatization were randomly divided into two equal groups: study group: the sinus membrane was elevated with bone marrow aspirate concentrate loaded on bovine graft whereas the control group recieved bovine graft only for sinus floor augmentation.
All patients will be evaluated at 1 week, 4 months by CBCT to measure bone height and bone core biopsy for histological assessment at 4 months during implant placement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BMAC/bovine graft | Active Comparator | Bone marrow aspirate concentrate loaded on bovine graft (Tutogen Medical GmbH, Neunkirchen am Brand, Germany, 1- 2mm particle size) utilization for sinus floor augmentation with residual alveolar bone height less than 5 mm, 1st arm |
|
| Bovine graft group | Active Comparator | bovine graft utilization for sinus floor augmentation with residual alveolar bone height less than 5 mm, 2nd arm |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BMAC loaded on bovine graft | Drug | Bone marrow aspirate concentrate loaded on bovine graft for sinus floor augmentation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Histological assessment | Histological assessment of core biopsy obtained at time of implant placement for percentage of new bone formation and residual graft | After 4 months of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Implant stability | implant stability immediately following installation after 4 months using ostell device (ISQ scale) | After 4 months of surgery |
| Bone gain | Vertical bone height gain from sinus floor on cone beam ct |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Maha Hakam, Phd | Professor at Faculty of Dentistry Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, department of oral and Maxillofacial Surgery | Cairo | 02 | Egypt |
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| Bovine graft only | Drug | Bovine graft only for sinus floor augmentation |
|
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| Preoperative, immediate and 4 months Postoperative |