Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.

Inclusion Criteria:

• patients from the FECCO (NCT04592003) cohort experiencing perprocedural or delayed perforation
• age over 18 years old

Exclusion Criteria:

• patients refusing exploitations of health datas
• patient treated with endoscopic mucosal resection

all adults patients identified from the FECCO (NCT04592003) cohort experciencing perprocedural or delayed perforation