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Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly. Little is known on the type of peripheral nerve block to perform so that optimal postoperative analgesia is provided with minimum impact on the motor function. This randomised controlled double-blinded trial tested the hypothesis that a femoral nerve block provides superior analgesia than a sciatic nerve block after proximal tibial osteotomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Femoral nerve block | Active Comparator | Femoral nerve block performed under ultrasound guidance with ropivacaine 0.5%, 20mL |
|
| Sciatic nerve block | Experimental | Sciatic nerve block performed under ultrasound guidance with ropivacaine 0.5%, 20mL |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Femoral nerve block with ropivacaine 0.5%, 20 ml | Procedure | Femoral nerve block under ultrasound guidance with ropivacaine 0.5%, 20 ml |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intravenous morphine consumption | Intravenous morphine consumption (mg) | 24 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Intravenous morphine consumption | Intravenous morphine consumption (mg) | 2 hours after surgery |
| Intravenous morphine consumption | Intravenous morphine consumption (mg) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital of Lausanne | Lausanne | Canton of Vaud | 1011 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38134484 | Derived | Kull C, Martin R, Rossel JB, Nguyen A, Albrecht E. Femoral vs sciatic nerve block to provide analgesia after medial open wedge high tibial osteotomy in the setting of multimodal analgesia: A randomized, controlled, single-blinded trial. J Clin Anesth. 2024 May;93:111355. doi: 10.1016/j.jclinane.2023.111355. Epub 2023 Dec 21. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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Two groups: femoral nerve block or sciatic nerve block with ropivacaine
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| Sciatic nerve block with ropivacaine 0.5%, 20 ml | Procedure | Sciatic nerve block under ultrasound guidance with ropivacaine 0.5%, 20 ml |
|
| 48 hours after surgery |
| rest pain score | pain score at rest (visual analogue scale, 0-10) | 2 hours after surgery |
| rest pain score | pain score at rest (visual analogue scale, 0-10) | 24 hours after surgery |
| rest pain score | pain score at rest (visual analogue scale, 0-10) | 48 hours after surgery |
| dynamic pain score | pain score on movement (visual analogue scale, 0-10) | 2 hours after surgery |
| dynamic pain score | pain score on movement (visual analogue scale, 0-10) | 24 hours after surgery |
| dynamic pain score | pain score on movement (visual analogue scale, 0-10) | 48 hours after surgery |
| Rate of postoperative nausea and vomiting | number of events/total number of patients | 2 hours after surgery |
| Rate of postoperative nausea and vomiting | number of events/total number of patients | 24 hours after surgery |
| Rate of postoperative nausea and vomiting | number of events/total number of patients | 48 hours after surgery |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D000588 |
| Amines |