Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy

Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy

The goal of this clinical trial is to evaluate regional ventilation distribution in patients admitted to the intensive care unit after emergent laparotomy due to abdominal sepsis. The main question it aims to answer is:

• evaluate if patients admitted after an open abdomen strategy have a different regional ventilation distribution compared to patients in which abdomen is closed at the end of the procedure

Participants will undergo non-invasive monitoring (esophageal pressure and electrical impedance tomography) and an blood gas analysis samples.

Researchers will compare open abdomen group and closed abdomen group to see if the ventilation distribution pattern is different.

Inclusion Criteria:

• Age > 18 and < 90 years
• Admitted to the ICU after emergent laparotomy for abdominal sepsis
• Acute respiratory failure

Exclusion Criteria:

• Controindications to electrical impedance tomography monitoring
• body mass index > 40 kg/m2
• Haemodinamic instability
• Pneumothorax - Pneumomediastinum
• refusal to participate