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| Name | Class |
|---|---|
| University of Illinois at Chicago | OTHER |
| University of Texas at Austin | OTHER |
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Physical inactivity is associated with poor asthma control and quality of life, and greater health care utilization. Rates of physical inactivity, asthma, and asthma mortality among Black women are higher than those of their White counterparts. Our formative work identified barriers to PA among Black women with asthma including a lack of social support, self-efficacy, unsafe neighborhood and fear related to experiences with life-threatening asthma exacerbations. Given the unique barriers to PA and high rates of physical inactivity that are associated with poor asthma outcomes in Black women, there is an urgent need to optimize PA interventions for this population. The proposed study uses our theory-driven intervention (ACTION: A lifestyle physiCal acTivity Intervention for minOrity womeN with asthma) to deliver a 24-week lifestyle physical activity intervention designed for and by urban Black women with asthma. Participants will be recruited through two urban health care systems that care for a diverse urban Black populations. Participants will be randomized to one of two groups: 1) ACTION intervention (group sessions, physical activity self-monitoring and text-based support for goal-setting), or 2) education control (an individual asthma education session and text messages related to asthma education). Participants will be followed for an additional 24-weeks after the intervention to assess for the maintenance of intervention effects on asthma health outcomes. We are proposing an efficacy study that focuses on asthma outcomes (Aim 1A/B), explores behavioral mechanisms of the intervention (Aim 2) and assesses factors that influence its reach and implementation potential (Aim 3). This trial will provide the first ever evidence of the efficacy of a lifestyle physical activity intervention among urban Black women with asthma, a population that is understudied yet plagued by low levels of PA and poor health outcomes. Our study has high potential to advance clinical treatment of asthma, and further the mechanistic understanding of physical activity interventions in minority populations living in low-resourced urban environments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ACTION Intervention | Experimental | Orientation (week 0): 1 group session Induction phase (weeks 1-12): 8 weekly then 2 bi-weekly goal setting via text with health coach + 2 group sessions (week 5, 9) Adoptive phase (weeks 13-24): 2 monthly goal setting with remote health coach + 3 group sessions (week 13, 17, 21) Maintenance phase (weeks 25-48): 1 group session Outcome assessment (12-, 24-, and 48-weeks) |
|
| Education Control | Other | Orientation (week 0): 1 individual asthma education session Education texts: weekly (weeks 1-8), then bi-weekly (week 9-12), then monthly (weeks 13-24) Outcome assessments (12-, 24-, 48-weeks) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ACTION Intervention | Behavioral | Participants in the ACTION Intervention arm of the study will have group sessions, physical activity self-monitoring, text-based support for goal setting. Following this intervention participants will be followed for an additional 24-weeks to assess for the maintenance of intervention effects on asthma health outcomes. |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma Control Questionnaire | Validated questionnaire | 24-weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma Control Questionnaire | Validated questionnaire | 48-weeks |
| Mini-asthma quality of life questionnaire | Validated questionnaire | 24- and 48-weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sharmilee Nyenhuis, MD | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Illinois Chicago | Chicago | Illinois | 60607 | United States | ||
| University of Chicago |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23252987 | Background | Avallone KM, McLeish AC. Asthma and aerobic exercise: a review of the empirical literature. J Asthma. 2013 Mar;50(2):109-16. doi: 10.3109/02770903.2012.759963. Epub 2013 Jan 31. | |
| 19246716 | Background | Garcia-Aymerich J, Varraso R, Anto JM, Camargo CA Jr. Prospective study of physical activity and risk of asthma exacerbations in older women. Am J Respir Crit Care Med. 2009 Jun 1;179(11):999-1003. doi: 10.1164/rccm.200812-1929OC. Epub 2009 Feb 26. |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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|
| Education Control | Other | Participants in the Education Control arm of the study will receive and individual asthma education session and text messages related to asthma education. Following this intervention participants will be followed for an additional 24-weeks to assess for the maintenance of intervention effects on asthma health outcomes. |
|
| Asthma exacerbations | Self-reported measure | 24- and 48-weeks |
| Healthcare Utilization (ED, urgent care, and hospitalizations) | Self-reported measure | 24- and 48-weeks |
| Self-efficacy for walking scale | Survey | 24- and 48-weeks |
| Social support for exercise | Survey | 24- and 48-weeks |
| Self-regulation | Measured by exercise self-regulation questionnaire (SRQ-E) and step goals achieved | 24- and 48-weeks |
| Light Physical Activity | Physical activity measure. Measured by Actigraph GT3XP-BTLE waist-based Accelerometer. | 24-weeks |
| Moderate Physical Activity | Physical activity measure. Measured by Actigraph GT3XP-BTLE waist-based Accelerometer. | 24-weeks |
| Moderate-Vigorous Physical Activity | Physical activity measure. Measured by Actigraph GT3XP-BTLE waist-based Accelerometer. | 24-weeks |
| Vigorous Physical Activity | Physical activity measure. Measured by Actigraph GT3XP-BTLE waist-based Accelerometer. | 24-weeks |
| Daily Steps | Physical activity measure. Measured by Actigraph GT3XP-BTLE waist-based Accelerometer | 24-weeks |
| PWMAQ | Physical activity measure. Validated questionnaire | 24-weeks |
| Chicago |
| Illinois |
| 60637 |
| United States |
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| 38324365 | Derived | Davis E, Townsend E, Cavalier A, Chen YF, Edwards-Hart D, Kitsiou S, Kowalczyk W, Mansur I, Okpara E, Powell K, Press VG, Ramirez T, Salvo D, Sharp LK, Wright B, Nyenhuis SM. Physical Activity Intervention for Urban Black Women With Asthma: Protocol for a Randomized Controlled Efficacy Study. JMIR Res Protoc. 2024 Feb 7;13:e55700. doi: 10.2196/55700. |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D001519 | Behavior |