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| Name | Class |
|---|---|
| Ewha Womans University Mokdong Hospital | OTHER |
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The goal of this prospective observational study is to learn about in patients who need percutaneous coronary intervention for coronary artery disease. The main questions it aims to answer are:
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| Measure | Description | Time Frame |
|---|---|---|
| Differences in fractional flow reserve (FFR) according to angiographic findings after coronary artery balloon angioplasty | Coronary angiographic findings and fractional flow within 15 minutes after coronary balloon angioplasty are collected and analyzed. | 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of differences in fractional flow reserve (FFR) before and after lesions between coronary balloon angioplasty using a scoring balloon and a regular balloon | Determine whether a scoring balloon or a general balloon was used during balloon angioplasty, and analyze whether there is a difference in FFR depending on the balloon used. | 1 year |
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Inclusion Criteria:
(Note) If there are other lesions in the proximal area and the FFR of the distal lesion is collected, it is included in the selection target regardless of whether or not the proximal lesion was operated on.
Exclusion Criteria:
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Patients who met the inclusion criteria and underwent interventions, as determined by clinical necessity, using fractional blood flow reserve (FFR) after percutaneous coronary angiography (PCA) will be included in the study.
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| Name | Affiliation | Role |
|---|---|---|
| Bon-Kwon Koo, MD | Seoul National University Hospital | Study Chair |
| Bon-Kwon Koo, MD | Seoul National University Hospital | Study Director |
| Bon-Kwon Koo, MD | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ewha Womans University Mokdong Hospital | Seoul | South Korea | ||||
| Seou National University Hospital |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 1-year outcome | Relationship between major cardiac events within 1 year according to changes in pre- and post-lesional fractional flow reserve (FFR), steady-state pressure ratio, and quantitative flow analysis (QFR) values before and after coronary artery balloon angioplasty | 1 year |
| Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific minimum lumen area | Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific minimum lumen area (mm2) | 1 year |
| Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific plaque burden | Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific plaque burden (plaque burden = plaque cross-sectional area (CSA, mm2)+ media CSA / external elastic membrane CSA) | 1 year |
| Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific positive remodeling | Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific positive remodeling (remodeling ratio > 1.05). remodeling ratio (RR) = external elastic membrane (EEM) area lesion/EEM area proximal reference | 1 year |
| Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific attenuated plaque | Relationship between fractional blood flow reserve and intravascular ultrasound lesion-specific attenuated plaque Attenuated Plaque: Plaque seen in intravascular ultrasound with acoustic shadowing behind large, echolucent acute culprit lesion sites, in the absence of bright calcium. | 1 year |
| Seoul |
| South Korea |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |