| Primary | Total Number of RBCs Used Over Admission | | | Posted | | Mean | Standard Deviation | RBC Units | | Within the first 30 days after surgery. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| | | Title | Denominators | Categories |
|---|
| | | Title | Measurements |
|---|
| - OG0005.8± 6.5
- OG0016.7± 7.2
|
|
| |
| Primary | Total Number of Platelets Used Over Admission | | | Posted | | Mean | Standard Deviation | platelet units | | Within the first 30 days after surgery. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Primary | Total Number of Plasma Used Over Admission | | | Posted | | Mean | Standard Deviation | plasma units | | Within the first 30 days after surgery. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of Cryo Units Used Perioperatively | All products within 3 days | | Posted | | Mean | Standard Deviation | cryo units | | 3 days post procedure | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of RBCs Used Perioperatively | Number of RBC units transfused during perioperative period | | Posted | | Mean | Standard Deviation | RBC units | | 3 days post procedure | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of Plasma Used Perioperatively | | | Posted | | Mean | Standard Deviation | plasma units | | 3 days post procedure | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of Platelets Used Perioperatively | Number of platelet units transfused during perioperative period | | Posted | | Mean | Standard Deviation | platelet units | | 3 days post procedure | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Time From Operating Room (OR) Start Time to Start of Cryo Transfusion | | Only the cardiac population was included for this analysis. The data was not available for liver transplant patients, so liver transplant patients were excluded from the analysis. | Posted | | Median | Inter-Quartile Range | minutes | | procedure (Time from OR start time to start of cryo transfusion) | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Time From Cryo Order to Start of Transfusion | Time to cryo order time to start of cryo transfusion | | Posted | | Mean | Standard Deviation | minutes | | procedure (Time from cryo order to start of transfusion) | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of Cryo Units Wasted by Blood Bank | This captures the Cryoprecipitate units discarded. | The blood bank, which is required to follow its standard operating procedures, was not able to document wastage in a way which allowed the investigators to accurately attribute wastage to a specific arm of the study. Therefore, wastage could not be accurately calculated as intended in the study protocol. | Posted | | | | | | Daily, up to approximately 24 months | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Pre Transfusion FIBTEM Amplitude 10 Min After Start of Clot Formation | FIBTEM before transfusion, if anesthesiologist orders it. FIBTEM is a point of care laboratory test measuring fibrinogen contribution to a clot. It is part of ROTEM testing and helps providers determine if patients need fibrinogen supplementation during surgical bleeding. | Data for all participants was not available because pre-transfusion FIBTEMs were not clinically ordered for all participants by the treating anesthesiologists. Only participants with pre-transfusion FIBTEMs available were included in this analysis. | Posted | | Mean | Standard Deviation | mm | | Variable, but it is generally available within 15 minutes of the start of ROTEM testing. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Post Transfusion FIBTEM Amplitude at 10 Min After Start of Clot Formation | FIBTEM after transfusion, if anesthesiologist orders it. FIBTEM is a point of care laboratory test measuring fibrinogen contribution to a clot. It is part of ROTEM testing and helps providers determine if patients need fibrinogen supplementation during surgical bleeding. | Data were not available nor collected for this measure because anesthesiologists do not routinely order this for the investigators to have been able to collect it. | Posted | | | | | | Variable, but it is generally available within 15 minutes of the start of ROTEM testing. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Maximum Clot Firmness (MCF) | The maximum strength of a clot as determined by ROTEM testing. | Data for MCF were not collected since clinical decisions are not made based on this value as the measure assumed. As such, there are no data to report. Clinical decisions were made based on A10 (the clot amplitude measured 10 minutes after clot formation start), not the maximum clot firmness (MCF). As A10 was not a pre-specified measure for this protocol, there are no data to report. Data will never be collected for this Outcome Measure. | Posted | | | | | | Variable, but it is generally available within 1 hour of the start of ROTEM testing. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Pre-transfusion Fibrinogen Level | The fibrinogen measurement before cryoprecipitate is transfused. | Some data were not collected for this measure because anesthesiologists did not routinely order this test. | Posted | | Mean | Standard Deviation | mg/dL | | During surgery, within 3 hours of specimen receipt by laboratory. | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Highest Fibrinogen Level Within 24 Hours | | Some data were not collected for this measure because anesthesiologists did not always order this test. | Posted | | Mean | Standard Deviation | mg/dL | | Within 24 hours after surgery | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Lowest Fibrinogen Level Within 24 Hours | | Some data were not collected for this measure because anesthesiologists did not always order this test. | Posted | | Mean | Standard Deviation | mg/dL | | Within 24 hours after surgery | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Cumulative Volume in Drains After Surgery (e.g., Chest Tube for CV Surgery) at the Time of Removal | The cumulative volume in drains after surgery (e.g., chest tube for CV surgery) at the time of drain removal | This data were not available for collection in the electronic health record as intended by the investigators, as the data were not clinically documented. Therefore, the cumulative volume in drains after surgery could not be reported as intended in the study protocol. | Posted | | | | | | Up to approximately 3 days | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Volume in Drains (Chest Tube for CV Surgery) | | Only the cardiac population was included for this analysis. The clinical parameter is not applicable to liver transplant patients, so liver transplant patients were excluded from the analysis. | Posted | | Mean | Standard Deviation | mLs | | At 24 hours after surgery | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Time From End of Bypass Pump for CV Surgery | | Only for cardiac surgery patients. Liver transplant patients are not on bypass. | Posted | | Median | Inter-Quartile Range | hours | | Until end of surgery | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Length of Stay in OR | Operating room length of stay | | Posted | | Mean | Standard Deviation | minutes | | Duration of time in operating room | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Length of Stay in ICU | Participant length of stay in ICU setting | | Posted | | Mean | Standard Deviation | days | | During hospitalization, approximately 5 days to 30 days | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Length of Stay in Hospital | Overall length of stay in hospital | | Posted | | Mean | Standard Deviation | days | | During hospitalization, approximately 5 days to 30 days | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Need for Ventilator | | Not all values available in the electronic health record. | Posted | | Count of Participants | | Participants | | During hospitalization, approximately 5 days to 30 days | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Time on Ventilator | If participant was on ventilator, amount of time spent on ventilator | Not all values available in the electronic health record. | Posted | | Mean | Standard Deviation | days | | During hospitalization, approximately 5 days to 30 days | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Overall Cost of Cryo vs PR Cryo, When Factoring Wastage | Cost of traditional cryoprecipitate compared to PR Cryoprecipitate. | Not available due to unavailable confidential contractual information that would be needed to calculate cost. The contract between the blood suppliers and hospital is confidential, and therefore the investigators were not able to report on cost-related factors as intended in the study protocol. Data will never be collected for this Outcome Measure. | Posted | | | | | | Daily, approximately 24 months | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
|
| Secondary | Number of Participants That Experienced an Adverse Event of Fever | All participants that experience fevers that occur during the time frame | | Posted | | Count of Participants | | Participants | | Within 5 days of surgery start time | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
| |
| Secondary | Number of Participants That Experienced an Adverse Event of Infection | All participants that experience infections that occur during the time frame | | Posted | | Count of Participants | | Participants | | Within 5 days of surgery start time | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
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| Secondary | Number of Participants That Experienced an Adverse Event of Transfusion Reaction. | All participants that experience transfusion reactions that occur during the time frame | | Posted | | Count of Participants | | Participants | | Within 5 days of surgery start time | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
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| Secondary | Fibrinogen Level | Fibrinogen level most proximal to the end of surgery | Fibrinogen was not ordered by provider for every participant | Posted | | Mean | Standard Deviation | mg/dL | | Most proximal to end of procedure | | | | ID | Title | Description |
|---|
| OG000 | Patients Given Traditional Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given traditional cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Traditional Cryoprecipitate: This is the cryoprecipitate already currently being given to patients with a cryo order. | | OG001 | Patients Given PR Cryo | These are the liver transplant and cardiothoracic (LT and CT) patients that will be given PR cryo based on the randomization protocol. The blood bank will alternate use of PR cryo and regular cryo each month for all patients with a cryo order. All patients will receive either traditional cryo or PR cryo in a given month. Pathogen-Reduced Cryoprecipitate: This is the pathogen-reduced cryoprecipitate that is intended to be compared to the standard cryoprecipitate. |
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